[1950年至1990年间中国诊断性X射线工作者患白血病的风险]
[Risk of leukemia among diagnostic x-ray workers in China between 1950 and 1990].
作者信息
Wang J, Li B, Gao Z, Xu J, Zhang J
机构信息
Institute of Radiation Medicine, CAMS and PUMC, Tianjin 300192.
出版信息
Zhonghua Xue Ye Xue Za Zhi. 1997 Feb;18(2):84-6.
OBJECTIVE
To explore the relationship between radiation and leukemia.
METHODS
Leukemia incidences (1950-1990) in 27011 diagnostic X-ray workers and in 25782 other medical specialists employed between 1950 and 1980 in China were compared.
RESULTS
The relative risk (RR) of leukemia in the diagnostic X-ray workers was 2.25-fold (95% C1=1.59-3.09, P<0.001) higher than that in the control group. The average age of the emergence of leukemia was 10.4 years younger in X-ray workers than in control group. The peak incidence of leukemia in X-ray workers occurred 10-14 years after engaging in X-ray work. The highest RR of leukemia was found in those who were engaged in X-ray work before 1965 or at age under 20 years.
CONCLUSION
Incidence of Leukemia in X-ray workers increased and it was correlated with radiation dosage and duration.
目的
探讨辐射与白血病之间的关系。
方法
比较了1950年至1990年间27011名诊断性X射线工作者以及1950年至1980年间在中国受雇的25782名其他医学专家的白血病发病率。
结果
诊断性X射线工作者患白血病的相对风险（RR）比对照组高2.25倍（95%CI=1.59-3.09，P<0.001）。X射线工作者患白血病的平均发病年龄比对照组小10.4岁。X射线工作者白血病的发病高峰出现在从事X射线工作10-14年后。1965年以前或20岁以下从事X射线工作的人群中白血病的RR最高。
结论
X射线工作者白血病发病率增加，且与辐射剂量和照射时间相关。
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