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[脑血管疾病所致颅内出血患者的眼底出血——其临床意义]

[Fundus hemorrhage in patients with intracranial hemorrhage caused by cerebrovascular disease--its clinical significance].

作者信息

Takano S, Saito M, Miyasaka Y, Yada K, Kitahara T, Ohwada T, Takagi H

机构信息

Department of Neurosurgery, Kitasato University, Sagamihara, Japan.

出版信息

No To Shinkei. 1992 Jan;44(1):13-7.

PMID:1562380
Abstract

To clarify the significance of fundus hemorrhage in the acute stage of intracranial hemorrhage due to cerebrovascular disease (HCVD), the incidence of such hemorrhage (retinal, preretinal, and subhyaloid hemorrhage) was examined and its correlations with the severity of the disturbance of consciousness and the prognosis were investigated. Two hundred sixteen HCVD patients with intracranial hemorrhage were the subjects of this study, including 87 cases of subarachnoid hemorrhage (SAH), 60 cases of hypertensive intracerebral hemorrhage (HICH), 54 cases of arteriovenous malformation (AVM), and 15 cases of Moyamoya disease. Fundus hemorrhage was recognized in 41 cases of SAH (47%), 5 cases of HICH (8%), 3 cases of AVM (6%), and 2 cases of Moyamoya disease (13%). The incidence of fundus hemorrhage was significantly higher in SAH than in the other type of HCVD associated with intracranial hemorrhage. Among patients with severe disturbance of consciousness (JCS 100-300), fundus hemorrhage was recognized in 69% with SAH, 13% with HICH, 17% with AVM, and none with Moyamoya disease. Therefore, patients with both fundus hemorrhage and severe disturbance of consciousness in the acute stage are most likely to have SAH, but HICH and AVM should be also taken into consideration. In patients with slight disturbance of consciousness (JCS 0-30), fundus hemorrhage was only noted in SAH (27%) and not in other types of HCVD associated with intracranial hemorrhage. Thus, SAH is highly likely to be the primary HCVD associated with intracranial hemorrhage, if we recognize fundus hemorrhage in patients with slight disturbance of consciousness in the acute stage.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为阐明脑血管病所致颅内出血急性期眼底出血的意义,我们对这类出血(视网膜、视网膜前及玻璃膜下出血)的发生率进行了检查,并研究了其与意识障碍严重程度及预后的相关性。本研究以216例颅内出血的脑血管病患者为研究对象,包括87例蛛网膜下腔出血(SAH)、60例高血压性脑出血(HICH)、54例动静脉畸形(AVM)和15例烟雾病。SAH患者中有41例(47%)出现眼底出血,HICH患者中有5例(8%),AVM患者中有3例(6%),烟雾病患者中有2例(13%)。SAH患者眼底出血的发生率显著高于其他伴有颅内出血的脑血管病类型。在意识严重障碍(日本昏迷量表评分100 - 300)的患者中,SAH患者眼底出血的发生率为69%,HICH患者为13%,AVM患者为17%,烟雾病患者未出现。因此,急性期同时出现眼底出血和意识严重障碍的患者最有可能患有SAH,但也应考虑HICH和AVM。在意识轻度障碍(日本昏迷量表评分0 - 30)的患者中,仅SAH患者出现眼底出血(27%),其他伴有颅内出血的脑血管病类型未出现。因此,如果在急性期意识轻度障碍的患者中发现眼底出血,SAH很可能是主要的伴有颅内出血的脑血管病。(摘要截选至250字)

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