Deep Akash, Ghildiyal R, Kandian S, Shinkre N
Department of Pediatrics, T.N.Medical College and B.Y.L. Nair Hospital, Mumbai -400008, India.
Indian Pediatr. 2004 Dec;41(12):1238-46.
This study was conducted in PICU of a teaching hospital to estimate the incidence of nosocomial infections, establish the clinical and bacteriological profile and identify probable exogenous source from the environment and personnel. 95 suspected cases of nosocomial infections were studied prospectively, identified as per the guidelines laid down by CDC. The rate of nosocomial infections was 27.3% with an incidence of 16.2 per 100 patient days. The incidence of urinary, respiratory and intravascular catheter related infections was 56.52%, 34.78%, 10.52% respectively. Klebsiella (33.33%) was the most common isolate with maximum sensitivity to amikacin. During the study, an outbreak of MRSA nosocomial infection was encountered and the source was traced to portable suction pump. The risk of nosocomial infection was directly related to the duration of stay in the PICU and duration of placement of indwelling catheters,tubes.
本研究在一家教学医院的儿科重症监护病房（PICU）进行，旨在评估医院感染的发生率，确定临床和细菌学特征，并识别环境和人员中可能的外源性感染源。前瞻性地研究了95例疑似医院感染病例，按照美国疾病控制与预防中心（CDC）制定的指南进行识别。医院感染率为27.3%，每100个患者日的发病率为16.2。泌尿系统、呼吸道和血管内导管相关感染的发病率分别为56.52%、34.78%、10.52%。克雷伯菌（33.33%）是最常见的分离菌株，对阿米卡星的敏感性最高。在研究期间，遇到了耐甲氧西林金黄色葡萄球菌（MRSA）医院感染的暴发，感染源追溯到便携式吸引泵。医院感染的风险与在PICU的住院时间以及留置导管、管道的放置时间直接相关。
