Dolenský Bohumil, Valík Martin, Sýkora David, Král Vladimír
Department of Analytical Chemistry, Institute of Chemical Technology, Prague, Technická 5, 166 28 Praha 6, Czech Republic.
Org Lett. 2005 Jan 6;7(1):67-70. doi: 10.1021/ol047902f.
Derivatives of Tröger's base (TB) have played important roles in receptor construction due to their rigid V-shape. A new class of these compounds are the oligo-TBs, which can function as cavitands. Herein, we describe both stepwise and one-step (oligomerization) methods suitable for the preparation of linear oligo-TBs.
由于特罗格碱（TB）衍生物具有刚性的V形结构，因此在受体构建中发挥了重要作用。这类化合物的一个新类别是寡聚TB，它可以作为穴状配体发挥作用。在此，我们描述了适用于制备线性寡聚TB的逐步法和一步法（寡聚化）。
