Harvey Allison G, Schmidt D Anne, Scarnà Antonina, Semler Christina Neitzert, Goodwin Guy M
Department of Experimental Psychology, University of Oxford, UK.
Am J Psychiatry. 2005 Jan;162(1):50-7. doi: 10.1176/appi.ajp.162.1.50.
The authors investigated sleep-related functioning in euthymic patients with bipolar disorder.
Euthymic patients with bipolar disorder (N=20), patients with insomnia (N=20), and subjects with good sleep (N=20) were compared on data from interviews and questionnaires and on findings from eight consecutive days and nights of sleep diary keeping (subjective sleep estimate) and actigraphy (objective sleep estimate).
Seventy percent of the euthymic patients with bipolar disorder exhibited a clinically significant sleep disturbance. Compared with the other groups, the bipolar disorder group exhibited impaired sleep efficiency, higher levels of anxiety and fear about poor sleep, lower daytime activity levels, and a tendency to misperceive sleep. The bipolar disorder group held a level of dysfunctional beliefs about sleep that was comparable to that in the insomnia group and significantly higher than that in the good sleeper group.
Insomnia is a significant problem among euthymic patients with bipolar disorder. Components of cognitive behavior therapy for insomnia, especially stimulus control and cognitive therapy, may be a helpful adjunct to treatment for patients with bipolar disorder.
作者研究了双相情感障碍病情稳定患者的睡眠相关功能。
对双相情感障碍病情稳定患者（N = 20）、失眠患者（N = 20）和睡眠良好的受试者（N = 20）进行比较，比较内容包括访谈和问卷调查数据，以及连续八天昼夜记录的睡眠日记（主观睡眠评估）和活动记录仪记录（客观睡眠评估）结果。
70%的双相情感障碍病情稳定患者存在临床上显著的睡眠障碍。与其他组相比，双相情感障碍组睡眠效率受损，对睡眠不佳的焦虑和恐惧水平更高，白天活动水平更低，且存在睡眠感知错误倾向。双相情感障碍组对睡眠的功能失调信念水平与失眠组相当，且显著高于睡眠良好组。
失眠在双相情感障碍病情稳定患者中是一个重要问题。失眠认知行为疗法的组成部分，尤其是刺激控制和认知疗法，可能对双相情感障碍患者的治疗有辅助作用。
