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[新型血液纠正剂对失血性休克时心脏线粒体氧化的影响]

[Effect of new hemocorrectors on heart mitochondrial oxidation in hemorrhagic shock].

作者信息

Shevchenko L I, Ageeva G R

出版信息

Biomed Khim. 2004 Sep-Oct;50(5):471-6.

PMID:15628596
Abstract

In experimental model of hemorrhagic shock, the influence of new hemocorrectors, succinasole and sucksivil (1,4-naphtoquinone) on rabbit myocardial mitochondrial oxidation was studied. Both substances improved function of myocardial mitochondria. Administration of new hemocorrectors increased duration of life of animals subjected to hemorrhagic shock, improved hemodynamics, metabolism, normalized myocaidla mitochondrial functions and increased positive effect of shock therapy.

摘要

在失血性休克实验模型中,研究了新型血液纠正剂琥珀索和苏西维(1,4-萘醌)对兔心肌线粒体氧化的影响。两种物质均改善了心肌线粒体功能。给予新型血液纠正剂可延长失血性休克动物的存活时间,改善血液动力学、代谢,使心肌线粒体功能恢复正常,并增强休克治疗的积极效果。

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