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用于准分子激光原位角膜磨镶术后角膜瘢痕形成和变薄的自动板层治疗性角膜移植术

Automated lamellar therapeutic keratoplasty for post-PRK corneal scarring and thinning.

作者信息

Tan Donald T H, Ang Leonard P K

机构信息

Singapore National Eye Centre, National University of Singapore, Singapore.

出版信息

Am J Ophthalmol. 2004 Dec;138(6):1067-9. doi: 10.1016/j.ajo.2004.06.062.

Abstract

PURPOSE

To present the use of automated lamellar therapeutic keratoplasty (ALTK) for the treatment of post-photorefractive keratectomy (PRK) corneal scarring and thinning with significant residual myopia.

DESIGN

Interventional case report.

METHODS

A patient with high myopia of -12 diopters previously underwent PRK that resulted in corneal scarring, myopic regression, moderate loss of best-corrected visual acuity, a residual refractive error of -6.50/-1.00 x 175 degrees, and a remaining corneal thickness of 300 mum. ALTK was first performed to remove the scar and to augment corneal thickness, and a subsequent laser-assisted in-situ keratomileusis (LASIK) procedure was performed to correct the residual myopia.

RESULTS

ALTK effectively removed the corneal scar and augmented the corneal thickness to 639 mum. LASIK effectively treated the residual myopia, resulting in an unaided visual acuity of 20/25 and a stable refractive error of plano/-0.50 x 40 degrees. The ALTK interface remained clear throughout the follow-up period of 26 months.

CONCLUSION

ALTK may be a reasonable alternative to conventional penetrating keratoplasty in the treatment of post-PRK corneal scarring and thinning, with a moderate loss of best-corrected visual acuity, and LASIK can be subsequently performed to correct the residual refractive error and achieve an excellent refractive and visual outcome.

摘要

目的

介绍使用自动板层治疗性角膜移植术(ALTK)治疗准分子激光角膜切削术(PRK)后角膜瘢痕形成、变薄并伴有显著残余近视的情况。

设计

介入性病例报告。

方法

一名患有-12屈光度高度近视的患者先前接受了PRK,导致角膜瘢痕形成、近视回退、最佳矫正视力中度下降、残余屈光不正为-6.50/-1.00×175度,剩余角膜厚度为300μm。首先进行ALTK以去除瘢痕并增加角膜厚度,随后进行准分子激光原位角膜磨镶术(LASIK)以矫正残余近视。

结果

ALTK有效去除了角膜瘢痕,并将角膜厚度增加至639μm。LASIK有效治疗了残余近视,裸眼视力达到20/25,屈光不正稳定在平光/-0.50×40度。在26个月的随访期内,ALTK界面始终保持清晰。

结论

在治疗PRK后角膜瘢痕形成、变薄且最佳矫正视力中度下降的情况时,ALTK可能是传统穿透性角膜移植术的合理替代方法,随后可进行LASIK以矫正残余屈光不正并获得优异的屈光和视觉效果。

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