Catania S, Zurrida S, Veronesi P, Galimberti V, Bono A, Pluchinotta A
Second Division of Surgery, Ospedale Vittore Buzzi, Milan, Italy.
Cancer. 1992 May 1;69(9):2267-70. doi: 10.1002/1097-0142(19920501)69:9<2267::aid-cncr2820690910>3.0.co;2-u.
Mondor's disease or thrombophlebitis of the subcutaneous veins of the chest region is an uncommon condition and is rarely associated with breast cancer. From January 1980 to June 1990, 63 cases of Mondor's disease were diagnosed (57 women and 6 men). In 31 patients, no apparent cause was determined (primary disease), whereas in 32 cases, the disease was secondary because the etiopathogenesis could be discerned. The identified potential causes were three cases of myentasis (all in men), eight cases of accidental local trauma (seven in women), seven cases of iatrogenic origin (three surgical breast biopsies, one skin biopsy, one needle biopsy, one mastectomy, and one reconstruction operation), six cases of inflammatory process, and eight cases associated with breast cancer (all females). Three of the tumors were less than 1 cm in diameter. The authors performed conservative surgery in four patients and demolitive in the other four. In this series, the incidence of breast cancer in association with Mondor's disease was the highest yet reported (12.7%). It was concluded that Mondor's disease may at times be caused by breast carcinoma. This association is by no means exceptional and implies that mammography should always be performed for Mondor's disease, even when the results of a physical examination are negative.
蒙多氏病或胸部皮下静脉血栓性静脉炎是一种罕见病症，很少与乳腺癌相关。1980年1月至1990年6月，共诊断出63例蒙多氏病患者（57名女性和6名男性）。31例患者未确定明显病因（原发性疾病），而在32例中，由于可识别病因发病机制，该疾病为继发性。已确定的潜在病因包括3例肌肉伸展过度（均为男性）、8例意外局部创伤（7例为女性）、7例医源性病因（3例乳腺手术活检、1例皮肤活检、1例针吸活检、1例乳房切除术和1例重建手术）、6例炎症过程以及8例与乳腺癌相关（均为女性）。其中3个肿瘤直径小于1厘米。作者对4例患者进行了保守手术，对另外4例进行了根治性手术。在该系列中，与蒙多氏病相关的乳腺癌发病率是迄今报道的最高值（12.7%）。得出的结论是，蒙多氏病有时可能由乳腺癌引起。这种关联绝非罕见，这意味着即使体格检查结果为阴性，对于蒙多氏病患者也应始终进行乳房X线摄影检查。
