Zhao Wei, Wang Jian-hua
Tianjin Medical University, Tianjin 300070, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2004 Oct;25(10):845-7.
To study the risk factors of pregnancy-induced hypertension syndrome (PIH) and their interactions and to develop measures to prevent PIH and related obstetrical complications.
Of 3205 pregnant women, 219 cases were found to have PIH. Data were gathered through questionnaires and measurement. Non-conditional logistic regression was used to identify the risk factors of PIH.
Single-factor logistic showed that age and family income were related to PIH. When family had history of hypertension, an increased incidence was seen. Parity and history of natural abortion increased the incidence of PIH. The risk for PIH increased significantly with factors related to heavier weight during pregnancy. Multi-factors non-conditional logistic regression showed that age (OR = 1.801, 95% CI: 1.106 - 2.934), number of natural abortion (OR = 8.955, 95% CI: 4.118 - 19.427), family history of hypertension (OR = 8.955, 95% CI: 4.118 - 19.427), weight during pregnancy (OR = 3.062, 95% CI: 1.619 - 5.905) were related to the risks of PIH.
It is necessary to strengthen screening program when women with advanced age, family history of hypertension, the numbers of natural abortion, weight of pregnancy in the PIH prevention strategy.
研究妊娠高血压综合征(PIH)的危险因素及其相互作用,并制定预防PIH及相关产科并发症的措施。
在3205名孕妇中,发现219例患有PIH。通过问卷调查和测量收集数据。采用非条件logistic回归分析确定PIH的危险因素。
单因素logistic分析显示,年龄和家庭收入与PIH有关。家族有高血压病史时,发病率增加。产次和自然流产史增加了PIH的发病率。PIH风险随孕期体重增加相关因素而显著增加。多因素非条件logistic回归分析显示,年龄(OR = 1.801,95%CI:1.106 - 2.934)、自然流产次数(OR = 8.955,95%CI:4.118 - 19.427)、高血压家族史(OR = 8.955,95%CI:4.118 - 19.427)、孕期体重(OR = 3.062,95%CI:1.619 - 5.905)与PIH风险有关。
在PIH预防策略中,对于高龄、有高血压家族史、有自然流产史、孕期体重增加的女性,有必要加强筛查项目。