Mendelsohn Colleen L, Griffin Craig E, Rosenkrantz Wayne S, Brown Larry D, Boord Mona J
Animal Dermatology Clinics, Tustin, California 92780, USA.
J Am Anim Hosp Assoc. 2005 Jan-Feb;41(1):12-21. doi: 10.5326/0410012.
The purpose of this 2-week, double-blinded, controlled clinical trial was to evaluate the efficacy of topical amino acid-complexed zinc gluconate formulated with boric acid (ZGB) or acetic acid (ZGA) versus a topical placebo in the treatment of yeast otitis externa in dogs. Included in the study were dogs with otitis externa and a cytopathological finding of yeast organisms in the affected ear. Ears were treated with the placebo, ZGA, or ZGB medications. Yeast counts as well as clinical appearance of the ears were monitored. Results revealed that ZGB significantly reduced the number of yeast organisms in cases of otitis externa.
这项为期两周的双盲对照临床试验的目的是评估与外用安慰剂相比，用硼酸（ZGB）或醋酸（ZGA）配制的外用氨基酸复合葡萄糖酸锌治疗犬酵母菌性外耳炎的疗效。该研究纳入了患有外耳炎且患耳细胞病理学检查发现酵母菌的犬只。对患耳使用安慰剂、ZGA或ZGB药物进行治疗。监测酵母菌计数以及耳部的临床表现。结果显示，ZGB能显著减少外耳炎病例中的酵母菌数量。
