文献检索
文档翻译
深度研究
学术资讯

Zotero 插件

邀请有礼
套餐&价格
历史记录

应用&插件

Zotero 插件浏览器插件 Mac 客户端 Windows 客户端微信小程序

定价

高级版会员购买积分包购买API积分包

服务

文献检索文档翻译深度研究 API 文档 MCP 服务

关于我们

关于 Suppr 公司介绍联系我们用户协议隐私条款

关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1

PCR amplification with primers based on IS2404 and GC-rich repeated sequence reveals polymorphism in Mycobacterium ulcerans.基于IS2404和富含GC的重复序列的引物进行PCR扩增，揭示了溃疡分枝杆菌的多态性。

J Clin Microbiol. 2005 Jan;43(1):448-51. doi: 10.1128/JCM.43.1.448-451.2005.

2

Identification of a new variable number tandem repeat locus in Mycobacterium ulcerans for potential strain discrimination among African isolates.在溃疡分枝杆菌中鉴定一个新的可变数目串联重复序列位点，用于区分非洲分离株中的潜在菌株。

Clin Microbiol Infect. 2007 Jul;13(7):734-6. doi: 10.1111/j.1469-0691.2007.01716.x. Epub 2007 Apr 2.

3

Evaluation of VNTR typing for the identification of Mycobacterium ulcerans in environmental samples from Victoria, Australia.澳大利亚维多利亚州环境样本中溃疡分枝杆菌鉴定的可变数目串联重复序列分型评估

FEMS Microbiol Lett. 2008 Oct;287(2):250-5. doi: 10.1111/j.1574-6968.2008.01328.x. Epub 2008 Aug 27.

4

A simple PCR method for rapid genotype analysis of Mycobacterium ulcerans.一种用于快速分析溃疡分枝杆菌基因型的简单聚合酶链反应方法。

J Clin Microbiol. 2000 Apr;38(4):1482-7. doi: 10.1128/JCM.38.4.1482-1487.2000.

5

[Contribution of gene amplification in Mycobacterium ulcerans detection in exudates and cutaneous biopsies in Côte d'Ivoire].[基因扩增在科特迪瓦渗出液和皮肤活检中溃疡分枝杆菌检测中的作用]

Bull Soc Pathol Exot. 2004 May;97(2):95-6.

6

Evaluation of PCR-restriction profile analysis and IS2404 restriction fragment length polymorphism and amplified fragment length polymorphism fingerprinting for identification and typing of Mycobacterium ulcerans and M. marinum.评价聚合酶链反应-限制性酶切图谱分析、IS2404限制性片段长度多态性及扩增片段长度多态性指纹图谱用于溃疡分枝杆菌和海分枝杆菌的鉴定及分型。

J Clin Microbiol. 2001 Sep;39(9):3272-8. doi: 10.1128/JCM.39.9.3272-3278.2001.

7

Genotyping Mycobacterium ulcerans and Mycobacterium marinum by using mycobacterial interspersed repetitive units.利用分枝杆菌散布重复单位对溃疡分枝杆菌和海分枝杆菌进行基因分型。

J Bacteriol. 2005 Mar;187(5):1639-47. doi: 10.1128/JB.187.5.1639-1647.2005.

8

The use of IS2404 restriction fragment length polymorphisms suggests the diversity of Mycobacterium ulcerans from different geographical areas.IS2404限制性片段长度多态性的应用表明来自不同地理区域的溃疡分枝杆菌具有多样性。

Am J Trop Med Hyg. 2001 May-Jun;64(5-6):270-3. doi: 10.4269/ajtmh.2001.64.270.

9

Multilocus variable-number tandem repeat typing of Mycobacterium ulcerans.溃疡分枝杆菌多位点可变数目串联重复序列分型

J Clin Microbiol. 2005 Apr;43(4):1546-51. doi: 10.1128/JCM.43.4.1546-1551.2005.

10

Development and application of two multiplex real-time PCR assays for the detection of Mycobacterium ulcerans in clinical and environmental samples.两种用于检测临床和环境样本中溃疡分枝杆菌的多重实时荧光定量PCR检测方法的开发与应用

Appl Environ Microbiol. 2007 Aug;73(15):4733-40. doi: 10.1128/AEM.02971-06. Epub 2007 May 25.

引用本文的文献

1

Comparative Genomics Shows That Mycobacterium ulcerans Migration and Expansion Preceded the Rise of Buruli Ulcer in Southeastern Australia.比较基因组学表明，溃疡分枝杆菌的迁移和扩张先于东南澳大利亚的布鲁里溃疡的出现。

Appl Environ Microbiol. 2018 Apr 2;84(8). doi: 10.1128/AEM.02612-17. Print 2018 Apr 15.

2

Detection of Mycobacterium ulcerans by real-time PCR with improved primers.使用改良引物通过实时聚合酶链反应检测溃疡分枝杆菌

Trop Med Health. 2016 Aug 19;44(1):28. doi: 10.1186/s41182-016-0028-3. eCollection 2016.

3

Development of a temperature-switch PCR-based SNP typing method for Mycobacterium ulcerans.基于温度开关 PCR 的溃疡分枝杆菌 SNP 分型方法的建立。

PLoS Negl Trop Dis. 2012;6(11):e1904. doi: 10.1371/journal.pntd.0001904. Epub 2012 Nov 15.

4

Single nucleotide polymorphism typing of Mycobacterium ulcerans reveals focal transmission of buruli ulcer in a highly endemic region of Ghana.结核分枝杆菌单核苷酸多态性分型显示在加纳高度流行地区存在局部传播的溃疡分枝杆菌感染。

PLoS Negl Trop Dis. 2010 Jul 20;4(7):e751. doi: 10.1371/journal.pntd.0000751.

5

Genomic diversity and evolution of Mycobacterium ulcerans revealed by next-generation sequencing.通过下一代测序揭示的溃疡分枝杆菌的基因组多样性与进化

PLoS Pathog. 2009 Sep;5(9):e1000580. doi: 10.1371/journal.ppat.1000580. Epub 2009 Sep 11.

6

Single nucleotide polymorphisms on the road to strain differentiation in Mycobacterium ulcerans.在溃疡分枝杆菌菌株分化的道路上的单核苷酸多态性。

J Clin Microbiol. 2009 Nov;47(11):3647-52. doi: 10.1128/JCM.00761-09. Epub 2009 Sep 2.

7

Lack of insertional-deletional polymorphism in a collection of Mycobacterium ulcerans isolates from Ghanaian Buruli ulcer patients.加纳溃疡分枝杆菌患者来源的分离株中缺乏插入缺失多态性。

J Clin Microbiol. 2009 Nov;47(11):3640-6. doi: 10.1128/JCM.00760-09. Epub 2009 Sep 2.

8

First cultivation and characterization of Mycobacterium ulcerans from the environment.首次从环境中分离培养溃疡分枝杆菌并进行生物学特性鉴定。

PLoS Negl Trop Dis. 2008 Mar 26;2(3):e178. doi: 10.1371/journal.pntd.0000178.

9

Independent loss of immunogenic proteins in Mycobacterium ulcerans suggests immune evasion.溃疡分枝杆菌中免疫原性蛋白的独立缺失表明其存在免疫逃逸。

Clin Vaccine Immunol. 2008 Apr;15(4):598-606. doi: 10.1128/CVI.00472-07. Epub 2008 Feb 6.

10

Ongoing genome reduction in Mycobacterium ulcerans.溃疡分枝杆菌正在进行的基因组缩减

Emerg Infect Dis. 2007 Jul;13(7):1008-15. doi: 10.3201/eid1307.060205.

本文引用的文献

1

PCR-based genotyping of Mycobacterium tuberculosis with new GC-rich repeated sequences and IS6110 inverted repeats used as primers.基于聚合酶链反应（PCR）的结核分枝杆菌基因分型，使用富含鸟嘌呤-胞嘧啶（GC）的新重复序列和插入序列6110（IS6110）反向重复序列作为引物。

J Clin Microbiol. 2004 Jan;42(1):372-7. doi: 10.1128/JCM.42.1.372-377.2004.

2

Characterization of an unusual Mycobacterium: a possible missing link between Mycobacterium marinum and Mycobacterium ulcerans.一种不寻常分枝杆菌的特性：海洋分枝杆菌与溃疡分枝杆菌之间可能缺失的环节

J Clin Microbiol. 2002 Jul;40(7):2370-80. doi: 10.1128/JCM.40.7.2370-2380.2002.

3

Evaluation of PCR-restriction profile analysis and IS2404 restriction fragment length polymorphism and amplified fragment length polymorphism fingerprinting for identification and typing of Mycobacterium ulcerans and M. marinum.评价聚合酶链反应-限制性酶切图谱分析、IS2404限制性片段长度多态性及扩增片段长度多态性指纹图谱用于溃疡分枝杆菌和海分枝杆菌的鉴定及分型。

J Clin Microbiol. 2001 Sep;39(9):3272-8. doi: 10.1128/JCM.39.9.3272-3278.2001.

4

The use of IS2404 restriction fragment length polymorphisms suggests the diversity of Mycobacterium ulcerans from different geographical areas.IS2404限制性片段长度多态性的应用表明来自不同地理区域的溃疡分枝杆菌具有多样性。

Am J Trop Med Hyg. 2001 May-Jun;64(5-6):270-3. doi: 10.4269/ajtmh.2001.64.270.

5

Comparative genetic analysis of Mycobacterium ulcerans and Mycobacterium marinum reveals evidence of recent divergence.溃疡分枝杆菌和海分枝杆菌的比较遗传分析揭示了近期分化的证据。

J Bacteriol. 2000 Nov;182(22):6322-30. doi: 10.1128/JB.182.22.6322-6330.2000.

6

A simple PCR method for rapid genotype analysis of Mycobacterium ulcerans.一种用于快速分析溃疡分枝杆菌基因型的简单聚合酶链反应方法。

J Clin Microbiol. 2000 Apr;38(4):1482-7. doi: 10.1128/JCM.38.4.1482-1487.2000.

7

Identification and characterization of IS2404 and IS2606: two distinct repeated sequences for detection of Mycobacterium ulcerans by PCR.IS2404和IS2606的鉴定与特性分析：用于通过PCR检测溃疡分枝杆菌的两种不同重复序列

J Clin Microbiol. 1999 Apr;37(4):1018-23. doi: 10.1128/JCM.37.4.1018-1023.1999.

8

Variability in 3' end of 16S rRNA sequence of Mycobacterium ulcerans is related to geographic origin of isolates.溃疡分枝杆菌16S rRNA序列3'端的变异性与分离株的地理来源有关。

J Clin Microbiol. 1996 Apr;34(4):962-5. doi: 10.1128/jcm.34.4.962-965.1996.

9

Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology.通过DNA指纹图谱技术进行结核分枝杆菌菌株鉴定：标准化方法建议

J Clin Microbiol. 1993 Feb;31(2):406-9. doi: 10.1128/jcm.31.2.406-409.1993.

10

Repeated DNA sequences in mycobacteria.分枝杆菌中的重复DNA序列。

Arch Microbiol. 1995 Feb;163(2):79-86. doi: 10.1007/BF00381780.

基于IS2404和富含GC的重复序列的引物进行PCR扩增，揭示了溃疡分枝杆菌的多态性。

PCR amplification with primers based on IS2404 and GC-rich repeated sequence reveals polymorphism in Mycobacterium ulcerans.

作者信息

Ablordey Anthony, Kotlowski Roman, Swings Jean, Portaels Françoise

机构信息

Mycobacteriology Unit, Institute of Tropical Medicine, B-2000 Antwerp, Belgium.

出版信息

J Clin Microbiol. 2005 Jan;43(1):448-51. doi: 10.1128/JCM.43.1.448-451.2005.

DOI:10.1128/JCM.43.1.448-451.2005

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC540136/

Abstract

We describe a simple genotyping method for Mycobacterium ulcerans based on PCR amplification of genomic regions between IS2404 and a frequently repeated GC-rich sequence. Application of this method to a global collection produced 10 M. ulcerans genotypes corresponding to their geographic origin.

摘要

我们描述了一种基于对IS2404与一个频繁重复的富含GC序列之间的基因组区域进行PCR扩增的溃疡分枝杆菌基因分型简单方法。将该方法应用于一个全球样本集，产生了10种与溃疡分枝杆菌地理来源相对应的基因型。