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[冲击波治疗胆囊结石。治疗现状]

[Shockwave treatment of gallbladder stones. Current status of therapy].

作者信息

Riemann J F, Weber J, Adamek H E, Buttmann A

机构信息

Medizinische Klinik C, Klinikum der Stadt Ludwigshafen/Rhein.

出版信息

Fortschr Med. 1992 Jan 20;110(1-2):37-8, 41-2.

PMID:1563697
Abstract

AIMS

Analysis of the results of piezoelectric lithotripsy of gallstones combined with subsequent dissolution therapy using chenodeoxycholic acid and ursodeoxycholic acid.

DESIGN OF STUDY

Retrospective evaluation after 2 1/2 years application in the department; prospective study for stone recurrence with ASA.

PATIENTS

A total of 246 patients with gallbladder stones selected on the basis of the Munich criteria; 171 patients were followed up for at least 24 months.

RESULTS

With piezoelectric shockwave lithotripsy treatment can mostly be carried out without the need for analgesia. When the indication is strictly applied, a stone-free rate of almost 90% after one year can be achieved. To achieve this, regular use of bile acids for dissolution of the fragments remaining after lithotripsy is required. At the present time, our recurrence rate is around 14% after one and two years. The use of acetylsalicylic acid recurrent stone prophylaxis was of no benefit.

CONCLUSIONS

Extracorporeal shockwave lithotripsy now forms a permanent part of the conservative therapeutic approach to cholecystolithiasis. The results obtained are largely dependent upon an accurate indication. Particularly suitable patients are those with solitary cholesterol stones in a properly functioning gallbladder.

摘要

目的

分析胆结石的压电碎石术联合随后使用鹅去氧胆酸和熊去氧胆酸进行溶石治疗的结果。

研究设计

在该科室应用2年半后进行回顾性评估;采用美国麻醉医师协会(ASA)标准对结石复发情况进行前瞻性研究。

患者

根据慕尼黑标准共选取246例胆囊结石患者;171例患者接受了至少24个月的随访。

结果

采用压电冲击波碎石术治疗时,大多数情况下无需镇痛即可进行。严格掌握适应症时,一年后结石清除率可达近90%。要达到这一效果,需要定期使用胆汁酸来溶解碎石后残留的碎片。目前,我们的一年和两年复发率约为14%。使用乙酰水杨酸预防结石复发并无益处。

结论

体外冲击波碎石术现已成为胆囊结石保守治疗方法的一个永久组成部分。所获得的结果在很大程度上取决于准确的适应症。特别适合的患者是胆囊功能正常的孤立性胆固醇结石患者。

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