Tau in neurodegenerative diseases: tau phosphorylation and assembly.
作者信息
Avila J, Pérez M, Lim F, Gómez-Ramos A, Hernández F, Lucas J J
机构信息
Centro de Biología Molecular Severo Ochoa (CSIC-UAM). Facultad de Ciencias.Campus de Cantoblanco. Universidad Autónoma de Madrid, 28049 Madrid, Spain.
出版信息
Neurotox Res. 2004;6(6):477-82. doi: 10.1007/BF03033284.
PMID:15639780
Abstract
The possible link between tau phosphorylation and tau assembly in these neurodegenerative diseases known as tauopathies is described. Additionally, this link is supported by an in vitro experiment showing the higher capacity of phosphotau to assemble in some specific conditions; and, by a recently reported experiment using a tau transgenic mouse model.
摘要
Zotero 插件