Vale J A, Kulig K
J Toxicol Clin Toxicol. 2004;42(7):933-43. doi: 10.1081/clt-200045006.
Gastric lavage should not be employed routinely, if ever, in the management of poisoned patients. In experimental studies, the amount of marker removed by gastric lavage was highly variable and diminished with time. The results of clinical outcome studies in overdose patients are weighed heavily on the side of showing a lack of beneficial effect. Serious risks of the procedure include hypoxia, dysrhythmias, laryngospasm, perforation of the GI tract or pharynx, fluid and electrolyte abnormalities, and aspiration pneumonitis. Contraindications include loss of protective airway reflexes (unless the patient is first intubated tracheally), ingestion of a strong acid or alkali, ingestion of a hydrocarbon with a high aspiration potential, or risk of GI hemorrhage due to an underlying medical or surgical condition. A review of the 1997 Gastric Lavage Position Statement revealed no new evidence that would require a revision of the conclusions of the Statement.
在中毒患者的治疗中,洗胃不应常规使用,即便使用也应谨慎。在实验研究中,洗胃清除的标志物量差异很大,且会随时间减少。过量用药患者的临床结局研究结果在很大程度上表明洗胃并无有益效果。该操作的严重风险包括缺氧、心律失常、喉痉挛、胃肠道或咽部穿孔、液体和电解质异常以及吸入性肺炎。禁忌证包括保护性气道反射丧失(除非患者先进行气管插管)、摄入强酸或强碱、摄入具有高吸入风险的碳氢化合物,或因潜在的内科或外科疾病而有胃肠道出血风险。对1997年洗胃立场声明的回顾显示,没有新的证据需要对该声明的结论进行修订。