Gregory W Thomas, Otto Lesley N, Bergstrom John O, Clark Amanda L
Obstetrics and Gynecology, Division of Urogynecology and Reconstructive Pelvic Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mail Code: L466, Portland, OR 97239, USA.
Int Urogynecol J Pelvic Floor Dysfunct. 2005 Sep-Oct;16(5):369-74. doi: 10.1007/s00192-004-1257-2. Epub 2005 Jan 12.
Nineteen women who had an abdominal sacrocolpopexy (ASC) with synthetic mesh and 18 women who had an ASC with freeze-dried, irradiated cadaveric fascia lata returned for blinded pelvic organ prolapse quantification (POPQ) examinations. The mean relative vaginal descent (delta) from perfect total vaginal length in the mesh group was 1.1 (0.3) cm, and the delta in the fascia group was 2.8 (0.8) cm (p=0.02, Mann-Whitney U). The proportion of women with "optimal" surgical outcome in the mesh group was 89% and 61% in the fascia group (p=0.06, Fischer's exact test). This study suggests that cadaveric fascia lata may not be a good choice for ASC.