Nakamura Hiroyuki, Hashimoto Toshio, Kusama Hiroshi, Sudoh Akihiko, Adachi Hideki, Yagyu Hisanaga, Kishi Koji, Oh-ishi Shuji, Matsuoka Takeshi
Fifth Department of Internal Medicine, Tokyo Medical University, Inashiki, Ibaraki.
Intern Med. 2004 Dec;43(12):1191-3. doi: 10.2169/internalmedicine.43.1191.
Primary mediastinal seminoma is a relatively rare tumor usually located in the anterior mediastinum. We report here an extremely rare case of a 66-year-old man with primary seminoma in the middle mediastinum. A physical examination showed lymphadenopathy in the right supraclavicular area. A chest CT confirmed the presence of a tumor occupying the retrotracheal space. A histological examination demonstrated metastatic seminoma from the open biopsy of the lymph node. Abdominal, pelvis, and cerebral CT scan and testicular ultrasound were negative. Thus, primary mediastinal seminoma in the middle mediastinum with supraclavicular lymph node metastasis was diagnosed.
原发性纵隔精原细胞瘤是一种相对罕见的肿瘤，通常位于前纵隔。我们在此报告一例极为罕见的病例，一名66岁男性患有位于中纵隔的原发性精原细胞瘤。体格检查发现右锁骨上区淋巴结肿大。胸部CT证实存在一个占据气管后间隙的肿瘤。组织学检查显示淋巴结开放活检为转移性精原细胞瘤。腹部、盆腔和脑部CT扫描以及睾丸超声检查均为阴性。因此，诊断为中纵隔原发性纵隔精原细胞瘤伴锁骨上淋巴结转移。
