Benesová P, Dĕdic K, Zák P, Voglová J
Fingerlandův ustav patologie, Fakultní nemocnice, Hradec Králové.
Cesk Patol. 2004 Oct;40(4):167-71.
The authors present a case of a 47-year-old man with idiopathic myelofibrosis. The diagnosis of myelofibrosis was made in 1981. Because of progression of the disease and failure of hematopoiesis in 2002, allogeneic peripheral blood stem cell transplantation was performed; the donor was an HLA identical relative. Six months after transplantation, trephin biopsies were made and a complete regression of bone marrow fibrosis was documented. It is the first case of this treatment for idiopathic myelofibrosis in the University Hospital in Hradec Králové.
作者报告了一例47岁的特发性骨髓纤维化男性患者。骨髓纤维化的诊断于1981年作出。由于疾病进展及2002年造血功能衰竭，进行了异基因外周血干细胞移植；供者为HLA配型相同的亲属。移植后6个月，进行了环钻活检，结果显示骨髓纤维化完全消退。这是赫拉德茨克拉洛韦大学医院首例采用这种方法治疗特发性骨髓纤维化的病例。
