Litkowski Leonard J, Quinlan Kathleen B, Ross David R, Ghassemi Annahita, Winston Anthony, Charig Andrew, Flickinger Mark, Vorwerk Linda
Department of Restorative Dentistry and Center for Clinical Studies, Dental School, University of Maryland, Baltimore, Maryland, USA.
Compend Contin Educ Dent. 2004 Sep;25(9 Suppl 1):25-31.
New dual-phase fluoride toothpastes that contain soluble calcium, phosphate, and baking soda have recently been introduced into the market. These toothpastes are designed to fill in small surface defects in tooth enamel and thereby enhance tooth esthetics such as gloss. This two-part study was designed to assess these superficial mineralizing effects from using one of these products compared with an experimental calcium-containing, bicarbonate-free formulation and a conventional fluoride toothpaste using an intraoral model. Enamel specimens with 4 types of defects were mounted into an intraoral appliance and placed in the mouths of volunteers for 1 month. The four types of defects were whitening toothpaste abrasion, coarse abrasion, natural dimpling, and acid etching. Before and after intraoral exposure, scanning electron microscope photographs of the specimens were made. The surface microhardness of the acid-etched specimens also was determined. The volunteers brushed their specimens twice daily with one of three randomly assigned toothpastes. The toothpastes were a two-phase, calcium-containing, bicarbonate-based toothpaste; an experimental, two-phase, calcium-containing, bicarbonate-free toothpaste; and a conventional toothpaste. Only the calcium-containing toothpastes showed unequivocal signs of mineral deposition into surface defects, leading to smoothing of the enamel. All three products significantly increased the hardness of the etched enamel, presumably because of fluoride. However, only the two calcium-containing toothpastes gave significantly greater hardness increases than the conventional toothpaste; the specimens treated with a conventional toothpaste were indistinguishable from those treated with saliva.
最近,市场上推出了含有可溶性钙、磷酸盐和小苏打成分的新型双相氟化物牙膏。这些牙膏旨在填补牙釉质表面的微小缺陷,从而提升牙齿美观度,比如光泽度。这项分为两部分的研究旨在通过口腔内模型,评估使用其中一种产品与一种不含碳酸氢盐的实验性含钙配方牙膏以及一种传统氟化物牙膏相比,所产生的这些表面矿化效果。将具有4种缺陷类型的牙釉质标本安装到口腔矫治器中,并放置在志愿者口中1个月。这4种缺陷类型分别是美白牙膏磨损、粗磨损、自然凹陷和酸蚀。在口腔暴露前后,对标本进行扫描电子显微镜拍照。还测定了酸蚀标本的表面显微硬度。志愿者每天用三种随机分配的牙膏之一刷牙两次。这三种牙膏分别是一种双相、含钙、含碳酸氢盐的牙膏;一种实验性的双相、含钙、不含碳酸氢盐的牙膏;以及一种传统牙膏。只有含钙牙膏显示出明确的矿物质沉积到表面缺陷中的迹象,从而使牙釉质变得光滑。所有三种产品都显著提高了酸蚀牙釉质的硬度,推测这是由于氟化物的作用。然而,只有这两种含钙牙膏的硬度增加幅度明显大于传统牙膏;用传统牙膏处理的标本与用唾液处理的标本没有区别。