Yang Weizhong, Zhou Dali, Yin Guangfu, Chen Huaiqing, Xiao Bin, Zhang Yun
College of Material Science and Engineering, Sichuan University, Chengdu 610065, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2004 Dec;21(6):913-6.
A novel glass-ceramic has been derived from sol-gel process. In this study XRD and FTIR analysis confirmed that the main crystalline phases of the material were hydroxyapatite/fluoroapatite [Ca10(PO4)6(OH,F)] and beta-wollastonite[beta-CaSiO3]; SEM examination showed that the microstructure contained many micro pores of 2-3 microm. After pore-forming, the material possessed good macro porous structure: the size of macro pores was 300-400 microm in diameter, and pores interconnected each other. Bioactivity of the material was preliminarily evaluated in the simulate body fluid. SEM observation revealed that a lot of apatite granules had been formed on the surface of the material after soaking within 7 days. Result shows that the novel sol-gel derived apatite-wollastonite-containing glass-ceramic has good bioactivity. Porous materials have suitable microstructure as well as macrostructure, which make it an excellent material to be used as bone-repairing materials and bone tissue engineering carrier materials.
一种新型微晶玻璃是通过溶胶-凝胶法制备的。在本研究中，XRD和FTIR分析证实该材料的主要晶相为羟基磷灰石/氟磷灰石[Ca10(PO4)6(OH,F)]和β-硅灰石[β-CaSiO3]；SEM检查表明，微观结构包含许多直径为2-3微米的微孔。成孔后，该材料具有良好的大孔结构：大孔直径为300-400微米，且孔相互连通。在模拟体液中对该材料的生物活性进行了初步评估。SEM观察显示，浸泡7天后材料表面形成了许多磷灰石颗粒。结果表明，新型溶胶-凝胶法制备的含磷灰石-硅灰石微晶玻璃具有良好的生物活性。多孔材料具有合适的微观结构和宏观结构，这使其成为用作骨修复材料和骨组织工程载体材料的优异材料。
