Nair K Sreekumaran
Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
J Ren Nutr. 2005 Jan;15(1):28-33. doi: 10.1053/j.jrn.2004.09.026.
Recent studies in humans have demonstrated the importance of the kidney in amino acid metabolism. In particular, it has been shown that conversion of phenylalanine to tyrosine occurs in the kidney and at a rate similar to that of the liver. Furthermore, unlike the liver, the kidney releases more tyrosine than it produces. In this review, the importance of this metabolic role of the kidney is discussed in context of chronic renal failure. The effect of renal failure on skeletal muscle protein metabolism is also discussed.
最近在人体中的研究表明了肾脏在氨基酸代谢中的重要性。特别是，已经证明苯丙氨酸向酪氨酸的转化发生在肾脏中，其速率与肝脏相似。此外，与肝脏不同，肾脏释放的酪氨酸比其产生的更多。在这篇综述中，将在慢性肾衰竭的背景下讨论肾脏这一代谢作用的重要性。还将讨论肾衰竭对骨骼肌蛋白质代谢的影响。
