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非体外循环冠状动脉搭桥术后房颤的预测因素。

Predictors of atrial fibrillation after off-pump coronary artery bypass graft surgery.

作者信息

Zangrillo Alberto, Landoni Giovanni, Sparicio Donatella, Benussi Stefano, Aletti Giacomo, Pappalardo Federico, Fracasso Giulia, Fano Greta, Crescenzi Giuseppe

机构信息

Department of Cardiovascular Anesthesia, IRCCS San Raffaele Hospital, Milan, Italy.

出版信息

J Cardiothorac Vasc Anesth. 2004 Dec;18(6):704-8. doi: 10.1053/j.jvca.2004.08.005.

Abstract

OBJECTIVE

Atrial fibrillation is the most common complication after coronary artery bypass graft surgery. This arrhythmia may lead to hemodynamic compromise, prolonged hospitalization, and increased risk for cerebral thromboembolism. Older age is the only variable consistently associated with the development of postoperative atrial fibrillation; however, no strong predictive model exists. The purpose of this study was to identify perioperative characteristics associated with new-onset atrial fibrillation in patients undergoing off-pump coronary artery bypass grafting.

DESIGN

Prospective, observational.

SETTING

University tertiary care hospital.

PARTICIPANTS

One hundred sixty consecutive patients undergoing off-pump coronary artery bypass grafting.

INTERVENTIONS

None.

MEASUREMENTS AND MAIN RESULTS

Incidence of postoperative atrial fibrillation was the major outcome. Atrial fibrillation occurred in 33 patients (20.6%). Multivariate analysis identified reintervention (odds ratio 26.8), revascularization of the ramus medianus (odds ratio 3.9), and age (odds ratio 1.069 per year) as the only independent predictors of postoperative atrial fibrillation. All patients were in sinus rhythm at hospital discharge. One hospital death was noted.

CONCLUSIONS

Despite the less invasive approach, the incidence of postoperative atrial fibrillation is high after off-pump coronary artery bypass grafting. Older age, grafting of the ramus medianus, and a redo operation were predictors of new-onset postoperative atrial fibrillation. It is possible that left atrial stretching with heart dislocation during revascularization of the lateral wall could lead to postoperative atrial fibrillation.

摘要

目的

心房颤动是冠状动脉旁路移植术后最常见的并发症。这种心律失常可能导致血流动力学不稳定、住院时间延长以及脑栓塞风险增加。高龄是与术后心房颤动发生始终相关的唯一变量;然而,尚无强大的预测模型。本研究的目的是确定非体外循环冠状动脉旁路移植术患者中新发心房颤动相关的围手术期特征。

设计

前瞻性观察性研究。

地点

大学三级护理医院。

参与者

160例连续接受非体外循环冠状动脉旁路移植术的患者。

干预措施

无。

测量指标及主要结果

术后心房颤动的发生率是主要观察指标。33例患者(20.6%)发生心房颤动。多因素分析确定再次干预(比值比26.8)、中间支血管重建(比值比3.9)和年龄(每年比值比1.069)是术后心房颤动仅有的独立预测因素。所有患者出院时均为窦性心律。记录到1例医院死亡。

结论

尽管采用了创伤较小的方法,但非体外循环冠状动脉旁路移植术后心房颤动的发生率仍很高。高龄、中间支血管移植和再次手术是术后新发心房颤动的预测因素。侧壁血管重建期间左心房因心脏移位而受牵拉可能导致术后心房颤动。

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