Zarcone R, Cardone G, Voto R I, Longo M, Cardone A
II Facoltà di Medicina, Università degli Studi Federico II di Napoli.
Minerva Ginecol. 1992 Mar;44(3):83-6.
The Authors point out the importance of histiocytes in Papanicolaou smears. Histiocytes are associated with endometrial carcinoma on tissue sections and may be seen on cervicovaginal smears as well. Smears obtained from 120 women, with clinical signs of endometrial diseases, were evaluated to determine the correlation between the presence of histiocytes in the cervicovaginal smears and endometrial adenocarcinoma. Histiocytes were quantified as minimal [less than 5 per high-power field (hpf)], moderate (5-10 hpf) or heavy (greater than 10/hpf). The histiocytes were found in smears from 80 women. Five adenocarcinomas, 9 hyperplasias were detected in 20 patients with moderate or heavy smears. The Authors conclude that the presence of histiocytes among postmenopausal women who have cervicovaginal smears should not be ignored. The data indicate that, in the absence of endometrial cells, histiocytes on cervicovaginal smears of postmenopausal women are associated with more elevated relative risk for endometrial carcinoma.
作者指出了组织细胞在巴氏涂片检查中的重要性。组织细胞在组织切片上与子宫内膜癌相关，在宫颈阴道涂片上也可能出现。对120名有子宫内膜疾病临床症状的女性所取的涂片进行评估，以确定宫颈阴道涂片中组织细胞的存在与子宫内膜腺癌之间的相关性。组织细胞被量化为少量（每高倍视野少于5个）、中度（5 - 10个/高倍视野）或大量（多于10个/高倍视野）。在80名女性的涂片中发现了组织细胞。在20名有中度或大量涂片的患者中检测到5例腺癌、9例增生。作者得出结论，绝经后女性宫颈阴道涂片中存在组织细胞这一情况不应被忽视。数据表明，在没有子宫内膜细胞的情况下，绝经后女性宫颈阴道涂片中的组织细胞与子宫内膜癌的相对风险升高有关。
