Petruzzi Massimo, De Benedittis Michele, Carriero Carmine, Giardina Carmela, Parisi Giuseppe, Serpico Rosario
Department of Odontostomatology and Surgery, University of Bari, Via Zara 1, 74100 Taranto, Italy.
Maturitas. 2005 Feb 14;50(2):140-50. doi: 10.1016/j.maturitas.2004.04.010.
Atrophic-erosive lichen planus with oral and genital involvement is a rare condition and is often difficult to diagnose. Patients seldom report genital symptoms to the dentist and dentists do not generally investigate about genital lesions. Delays in diagnosis may cause complications and affect the quality of life. We report the clinical and histopathological features of two new cases of oro-vaginal-vulvar lichen planus and review current treatment options for this condition. Genital lichen planus should be suspected in case of atrophic-erosive oral lichen planus. A thorough multidisciplinary medical management and active early treatment are necessary to improve symptoms and prevent genital sequelae. This might also be a relevant prevention strategy for the risk of squamous cell carcinoma, although data to fully support this statement still need investigation.
伴有口腔和生殖器受累的萎缩性糜烂性扁平苔藓是一种罕见疾病,常常难以诊断。患者很少向牙医报告生殖器症状,而牙医通常也不会对生殖器病变进行检查。诊断延误可能导致并发症并影响生活质量。我们报告了两例口腔-阴道-外阴扁平苔藓新病例的临床和组织病理学特征,并回顾了针对该疾病的当前治疗选择。如果存在萎缩性糜烂性口腔扁平苔藓,应怀疑有生殖器扁平苔藓。需要进行全面的多学科医疗管理和积极的早期治疗,以改善症状并预防生殖器后遗症。这也可能是预防鳞状细胞癌风险的一项相关策略,尽管充分支持这一说法的数据仍需研究。