Genadry René, Provost Thomas T
Department of Obstetrics and Gynecology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
J Reprod Med. 2006 Jan;51(1):67-72.
Oral lichen planus (LP) is thought to affect 1% of the population. It is an autoimmune inflammatory disease process with varied clinical manifestations. Glabrous skin scarring is rare, but that of mucosal membranes may be more common than recognized. It has been estimated that 25% of patients with oral lesions also harbor genital lesions.
We report 4 cases of LP with genital involvement treated at various stages of development. Severe mucosal scarring occurred, and vulvovaginal scarring commonly resulted in significant dyspareunia.
Early and aggressive diagnosis and therapy may abrogate the scarring potential of this debilitating disease process.
口腔扁平苔藓（LP）被认为影响1%的人口。它是一种具有多种临床表现的自身免疫性炎症性疾病过程。无毛皮肤瘢痕形成罕见，但黏膜瘢痕形成可能比公认的更为常见。据估计，25%的口腔病变患者也有生殖器病变。
我们报告4例在不同发展阶段接受治疗的伴有生殖器受累的LP病例。发生了严重的黏膜瘢痕形成，外阴阴道瘢痕形成通常导致严重的性交困难。
早期积极的诊断和治疗可能消除这种使人衰弱的疾病过程的瘢痕形成可能性。
Zotero 插件