伏立康唑在心脏移植术后侵袭性曲霉病治疗中优于两性霉素B。
Superiority of voriconazole over amphotericin B in the treatment of invasive aspergillosis after heart transplantation.
作者信息
Wieland Thomas, Liebold Andreas, Jagiello Magda, Retzl Gerald, Birnbaum Dietrich E
机构信息
University Hospital of Regensburg, Department of Cardiothoracic Surgery, Franz-Josef-Strauss-Allee 11, Regensburg 93053, Germany.
出版信息
J Heart Lung Transplant. 2005 Jan;24(1):102-4. doi: 10.1016/j.healun.2003.10.014.
Invasive aspergillosis in immuncompromised patients occurs frequently. Surgical therapy in combination with chemotherapy with amphotericin B and itraconazole is standard therapy. We describe a heart transplant recipient with invasive Aspergillus fumigatus infection in the lung, which was treated successfully with voriconazole after systemically high-dose intravenous therapy with amphotericin B failed.
免疫功能低下患者侵袭性曲霉病很常见。手术治疗联合两性霉素B和伊曲康唑化疗是标准治疗方法。我们描述了一名心脏移植受者，其肺部发生侵袭性烟曲霉感染，在两性霉素B全身大剂量静脉治疗失败后，用伏立康唑成功治愈。
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