伏立康唑在由对伊曲康唑耐药的烟曲霉菌株引起的曲菌球患者中的应用。
Use of voriconazole in a patient with aspergilloma caused by an itraconazole-resistant strain of Aspergillus fumigatus.
作者信息
Dannaoui E, Garcia-Hermoso D, Naccache J M, Meneau I, Sanglard D, Bouges-Michel C, Valeyre D, Lortholary O
机构信息
Université Paris Descartes, Faculté de Médecine, AP-HP, Hôpital Européen Georges Pompidou, Unité de Parasitologie - Mycologie, 75015 Paris, France.
Centre National de Référence Mycologie et Antifongiques, Unité de Mycologie Moléculaire, CNRS FRE2849, Institut Pasteur, 75724 Paris Cedex 15, France.
出版信息
J Med Microbiol. 2006 Oct;55(Pt 10):1457-1459. doi: 10.1099/jmm.0.46639-0.
The case is reported of a patient with cavitary sarcoidosis complicated by an aspergilloma caused by an itraconazole-resistant strain of Aspergillus fumigatus, who was treated with voriconazole. The authors suggest that susceptibility testing of A. fumigatus strains is of value during long-term therapy with itraconazole, and that voriconazole may be a good option for treatment of patients infected with itraconazole-resistant strains of A. fumigatus.
报告了1例空洞型结节病合并由耐伊曲康唑烟曲霉菌株引起的曲菌球患者，该患者接受了伏立康唑治疗。作者认为，在伊曲康唑长期治疗期间，对烟曲霉菌株进行药敏试验是有价值的，并且伏立康唑可能是治疗感染耐伊曲康唑烟曲霉菌株患者的一个良好选择。
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