Brecher Mark E, Hay Shauna N
Transfusion Medicine Service, CB 7600, University of North Carolina Hospitals, 101 Manning Dr., Chapel Hill, NC 27514, USA.
Clin Microbiol Rev. 2005 Jan;18(1):195-204. doi: 10.1128/CMR.18.1.195-204.2005.
Blood for transfusion is a potential source of infection by a variety of known and unknown transmissible agents. Over the last 20 years, astounding reductions in the risk of viral infection via allogeneic blood have been achieved. As a result of this success, bacterial contamination of blood products has emerged as the greatest residual source of transfusion-transmitted disease. This paper summarizes the current status of detection, prevention, and elimination of bacteria in blood products for transfusion.
用于输血的血液是多种已知和未知可传播病原体的潜在感染源。在过去20年里,通过异体输血感染病毒的风险已大幅降低。由于这一成果,血液制品的细菌污染已成为输血传播疾病最大的残留来源。本文总结了用于输血的血液制品中细菌检测、预防和清除的现状。