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BACTEC 9240与BacT/Alert血培养系统检测血小板浓缩物中细菌污染的比较。

Comparison of the BACTEC 9240 and BacT/Alert blood culture systems for detection of bacterial contamination in platelet concentrates.

作者信息

Riedel Stefan, Siwek Gregory, Beekmann Susan E, Richter Sandra S, Raife Thomas, Doern Gary V

机构信息

Division of Clinical Microbiology and Transfusion Medicine, Department of Pathology, University of Iowa College of Medicine, Iowa City, IA 52242, USA.

出版信息

J Clin Microbiol. 2006 Jun;44(6):2262-4. doi: 10.1128/JCM.00635-06.

DOI:10.1128/JCM.00635-06
PMID:16757635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1489399/
Abstract

The BACTEC 9240 blood culture system with a standard aerobic medium, Plus Aerobic/F, was compared to the BacT/Alert system with a platelet-specific medium, BPA, as a means for detecting bacterial contamination of platelet preparations. One hundred thirteen platelet units seeded with low levels of different bacteria were examined with both systems. In 93 instances, growth was detected first in the BACTEC system; in 12 cases, growth registered first in the BacT/Alert system. Among all comparisons, growth was detected, on average, 1.7 h sooner with the BACTEC system. The differences in length of time to detection were statistically significant.

摘要

将配备标准需氧培养基(Plus Aerobic/F)的BACTEC 9240血培养系统与配备血小板特异性培养基(BPA)的BacT/Alert系统进行比较,以此作为检测血小板制剂细菌污染的一种方法。用这两种系统检测了接种低水平不同细菌的113个血小板单位。在93例中,BACTEC系统首先检测到生长;在12例中,BacT/Alert系统首先记录到生长。在所有比较中,BACTEC系统平均比其他系统早1.7小时检测到生长。检测时间长度的差异具有统计学意义。

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本文引用的文献

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In-house validation of the BACTEC 9240 blood culture system for detection of bacterial contamination in platelet concentrates.BACTEC 9240血培养系统用于检测血小板浓缩物中细菌污染的室内验证
Transfusion. 2005 Jul;45(7):1138-42. doi: 10.1111/j.1537-2995.2005.04343.x.
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Bacterial contamination of blood components.血液成分的细菌污染
Clin Microbiol Rev. 2005 Jan;18(1):195-204. doi: 10.1128/CMR.18.1.195-204.2005.
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Impact of clinical practice guidelines on the clinical microbiology laboratory.临床实践指南对临床微生物学实验室的影响。
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Bacterial contamination of platelet units: a case report and literature survey with review of upcoming american association of blood banks requirements.
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Bacterial contamination of blood components: risks, strategies, and regulation: joint ASH and AABB educational session in transfusion medicine.血液成分的细菌污染:风险、策略与监管:美国血液学会(ASH)与美国血库协会(AABB)输血医学联合教育会议
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