同时性和异时性结直肠癌
Synchronous and metachronous colorectal carcinoma.
作者信息
Papadopoulos V, Michalopoulos A, Basdanis G, Papapolychroniadis K, Paramythiotis D, Fotiadis P, Berovalis P, Harlaftis N
机构信息
1st Propedeutic Surgical Clinic, Aristotle's University, AHEPA Hospital, Thessaloniki, Greece.
出版信息
Tech Coloproctol. 2004 Nov;8 Suppl 1:s97-s100. doi: 10.1007/s10151-004-0124-y.
BACKGROUND
Synchronous and metachronous colorectal carcinoma have an incidence of 2-10%. The purpose of the study was to evaluate the clinical characteristics, the accuracy of diagnostic examinations and the survival of these patients.
METHODS
From 1970 to 1999, 1160 patients with colorectal cancer were admitted to our Department. During follow-up examination 50 patients (4.3%) were found to present with multiple primary colon cancers. Fifty-two per cent were synchronous and 48% metachronous tumours.
RESULTS
The overall 5-year survival of the patients was 45.87%. Mortality was 10% for multiple primaries, while in patients with single cancer was 4.1%. The overall 5-year survival of the patients with multiple primaries tumours was 46.67%.
CONCLUSIONS
Patients with colorectal cancer must be fully studied endoscopically. There has been an improvement in survival in recent years due to better surgical techniques, the introduction of more sophisticated examination methods and the meticulous follow-up of patients at risk.
背景
同时性和异时性结直肠癌的发病率为2%-10%。本研究的目的是评估这些患者的临床特征、诊断检查的准确性和生存率。
方法
1970年至1999年，1160例结直肠癌患者入住我科。在随访检查中，发现50例患者（4.3%）患有多发性原发性结肠癌。52%为同时性肿瘤，48%为异时性肿瘤。
结果
患者的总体5年生存率为45.87%。多发性原发性肿瘤的死亡率为10%，而单发性癌症患者的死亡率为4.1%。多发性原发性肿瘤患者的总体5年生存率为46.67%。
结论
结直肠癌患者必须接受全面的内镜检查。近年来，由于手术技术的改进、更先进检查方法的引入以及对高危患者的精心随访，生存率有所提高。
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