Osipenko M F, Pankova L Iu, Vergazov V M
Klin Med (Mosk). 2004;82(11):35-8.
To assess the risk factors of mycotic infection on the gastric mucosa (GM) in patients with gastric peptic ulcer, 34 patients who had much mycelium on the bottom of the defect and 122 patients without fungal infection were examined in detail. The occurrence of mycotic infection in patients with ulcerative defects was associated with a variety of both local (the depth, number, large sizes of defects, diminished gastric acid-producing ability) and total (age, trophological insufficiency, iron-deficiency anemia, oral mycotic disease, autonomic dysfunction) factors. Mycotic involvement of ulcerative defects is secondary and regarded as a focal manifestation of mycotic infection. The likely impact of mycotic infection on the quality of ulcerative defect scarring makes us consider whether antimycotic agents should be added to antiulcerative therapy.
为评估胃溃疡患者胃黏膜真菌感染的危险因素，对34例溃疡底部有大量菌丝的患者和122例无真菌感染的患者进行了详细检查。溃疡缺损患者真菌感染的发生与多种局部因素（缺损的深度、数量、大小、胃酸分泌能力降低）和全身因素（年龄、营养不足、缺铁性贫血、口腔真菌病、自主神经功能障碍）有关。溃疡缺损的真菌累及是继发性的，被视为真菌感染的局灶性表现。真菌感染对溃疡缺损瘢痕形成质量的可能影响使我们考虑是否应在抗溃疡治疗中添加抗真菌药物。
