用于生物传感的碳纳米管和纳米线。

Carbon nanotubes and nanowires for biological sensing.

作者信息

Li Jun, Ng Hou Tee, Chen Hua

机构信息

Center for Nanotechnology, NASA Ames Research Center, Moffett Field, CA, USA.

出版信息

Methods Mol Biol. 2005;300:191-23. doi: 10.1385/1-59259-858-7:191.

DOI:10.1385/1-59259-858-7:191

PMID:15657485

Abstract

This chapter reviews the recent development in biological sensing using nanotechnologies based on carbon nanotubes and various nanowires. These 1D materials have shown unique properties that are efficient in interacting with biomolecules of similar dimensions, i.e., on a nanometer scale. Various aspects including synthesis, materials properties, device fabrication, biofunctionalization, and biological sensing applications of such materials are reviewed. The potential of such integrated nanobiosensors in providing ultrahigh sensitivity, fast response, and high-degree multiplex detection, yet with minimum sample requirements is demonstrated. This chapter is intended to provide comprehensive updated information for people from a variety of backgrounds but with common interests in the fast-moving interdisciplinary field of nanobiotechnology.

摘要

本章综述了基于碳纳米管和各种纳米线的纳米技术在生物传感方面的最新进展。这些一维材料展现出了独特的性质，能够在纳米尺度上与尺寸相近的生物分子高效相互作用。文中综述了此类材料的各个方面，包括合成、材料特性、器件制造、生物功能化以及生物传感应用。文中展示了此类集成纳米生物传感器在提供超高灵敏度、快速响应和高程度多重检测方面的潜力，同时对样品的需求量极小。本章旨在为来自不同背景、但对快速发展的纳米生物技术跨学科领域有着共同兴趣的人们提供全面的最新信息。