Graduate Institute of Medical Mechatronics, Department of Mechanical Engineering, Chang Gung University, Taoyuan, Taiwan, ROC.
Recent Pat Nanotechnol. 2013 Jan;7(1):81-90.
Microfluidic systems provide a total solution of biological and chemical analysis from the sample application to the display of the analysis results. A lot of developments on the point-of-care diagnostic applications have been reported and the commercial possibility is shown. To achieve sensitive and specific biological sensing, nanoparticles may provide a promising tool because they have similar length scale with the biomolecules. The nano-sensing technology suggests a molecular level detection of the biomolecules to pursue higher performance. In this review, recent developments and patents on the biological sensing using nanoparticles in microfluidic systems are discussed. An updated, systematic and rapid reference in the field of nano-biological sensing is provided.
微流控系统为从样品应用到分析结果显示的生物和化学分析提供了完整的解决方案。已经有很多关于即时诊断应用的开发，并展示了其商业可能性。为了实现灵敏和特异的生物传感，纳米颗粒可能提供了一种很有前途的工具，因为它们与生物分子具有相似的长度尺度。纳米传感技术提示了对生物分子的分子级检测，以追求更高的性能。在这篇综述中，讨论了在微流控系统中使用纳米颗粒进行生物传感的最新进展和专利。提供了该纳米生物传感领域的最新、系统和快速的参考。
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