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结肠和直肠血管肉瘤:1例报告并文献复习

Angiosarcoma of the colon and rectum: report of a case and review of the literature.

作者信息

Brown Carl J, Falck Vincent G, MacLean Anthony

机构信息

Department of Surgery, Foothills Medical Centre, University of Calgary, Calgary, Alberta, Canada.

出版信息

Dis Colon Rectum. 2004 Dec;47(12):2202-7. doi: 10.1007/s10350-004-0698-5.

Abstract

Angiosarcoma is a malignancy that occurs rarely in the gastrointestinal tract. We present a case of a 77-year-old male who had rectal bleeding and obstructive bowel symptoms. A large near-obstructing mass was seen endoscopically, but biopsies were inconclusive. A CT scan showed a large sigmoid lesion, and the patient had surgical resection. A large hemorrhagic-appearing tumor was found at operation. Angiosarcoma of the sigmoid colon was diagnosed on histologic examination. After colonic resection, the patient rapidly developed numerous liver metastases and died six months later. A review of the literature reveals only 12 other reported cases of colorectal angiosarcoma; 62 percent of these patients died within one year of surgical resection. The role of adjuvant radiation and/or chemotherapy is unclear. In conclusion, colorectal angiosarcomas are rare tumors that behave very aggressively, and the outcome is generally poor.

摘要

血管肉瘤是一种罕见于胃肠道的恶性肿瘤。我们报告一例77岁男性,他有直肠出血和肠梗阻症状。内镜检查发现一个大的近阻塞性肿物,但活检结果不明确。CT扫描显示乙状结肠有一个大病变,患者接受了手术切除。手术中发现一个外观呈出血性的大肿瘤。经组织学检查诊断为乙状结肠血管肉瘤。结肠切除术后,患者迅速出现多处肝转移,6个月后死亡。文献回顾显示,仅另有12例结直肠血管肉瘤的报告病例;这些患者中有62%在手术切除后一年内死亡。辅助放疗和/或化疗的作用尚不清楚。总之,结直肠血管肉瘤是罕见肿瘤,侵袭性很强,总体预后较差。

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