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以结肠息肉为特征的血管肉瘤:一例报告。

Angiosarcoma characterized by colonic polyps: A case report.

作者信息

Zhao Fei, Pan Hanghai, Wang XiaoGang

机构信息

Department of Gastroenterology.

Department of Nuclear Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Zhejiang, Province, China.

出版信息

Medicine (Baltimore). 2020 Oct 2;99(40):e22581. doi: 10.1097/MD.0000000000022581.

Abstract

RATIONALE

Angiosarcoma is a highly invasive tumour with a low incidence rate but high rates of local recurrence and distant metastasis and a poor prognosis. Understanding the endoscopic characteristics of angiosarcoma will help with early diagnosis and treatment of this disease.

PATIENT CONCERNS

The patient was a 77-year-old female who was admitted to the hospital due to recurring melena for 3 months. Outpatient gastroscopy showed that the patient had multiple gastric erosions. Colonoscopy revealed the presence of multiple protruding lesions in the colon and multiple rectal polyps. Pathological biopsy indicated that the patient had a tubular adenoma, which was removed by endoscopic resection.

DIAGNOSES

Postsurgical pathologic assessment suggested that the histological subtype was epithelioid angiosarcoma. Positron emission tomography-computed tomography (PET-CT) revealed multiple metastases in the lymph nodes and bone.

INTERVENTIONS

The patient underwent acid suppression to protect the stomach, fluid supplementation and red blood cell infusion, and subsequently, surgery, radiotherapy and chemotherapy were recommended. The patient's family refused further treatments for the patient and requested discharge.

OUTCOMES

The patient refused further treatment and was not followed-up.

LESSONS

Colorectal angiosarcoma is an extremely rare and highly malignant tumour, and understanding its endoscopic morphology will help aid in its diagnosis.

摘要

理论依据

血管肉瘤是一种侵袭性很强的肿瘤,发病率低,但局部复发和远处转移率高,预后较差。了解血管肉瘤的内镜特征将有助于该疾病的早期诊断和治疗。

患者情况

该患者为77岁女性,因反复黑便3个月入院。门诊胃镜检查显示患者有多处胃糜烂。结肠镜检查发现结肠有多处突出病变和多个直肠息肉。病理活检表明患者患有管状腺瘤,通过内镜切除。

诊断

术后病理评估提示组织学亚型为上皮样血管肉瘤。正电子发射断层扫描-计算机断层扫描(PET-CT)显示淋巴结和骨骼有多处转移。

干预措施

患者接受了抑酸以保护胃、补液和输注红细胞,随后建议进行手术、放疗和化疗。患者家属拒绝为患者进一步治疗并要求出院。

结果

患者拒绝进一步治疗且未进行随访。

经验教训

结直肠血管肉瘤是一种极其罕见且高度恶性的肿瘤,了解其内镜形态有助于诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f6f/7535772/427e957874ee/medi-99-e22581-g001.jpg

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