Finn Laura S, Argenyi Zsolt B
The Department of Pathology at The University of Washington, Seattle, WA 98105, USA.
J Cutan Pathol. 2005 Jan;32(1):59-62. doi: 10.1111/j.0303-6987.2005.00257.x.
The various forms of non-melanocytic nevi (hamartomas) are usually encountered in pediatric patients, and nevus sebaceous of Jadassohn is the most common to have undifferentiated pilosebaceous units. We report a unique congenital follicular nevus that fails to meet the criteria of any previously described follicular neoplasm, despite the plethora of alternatives. Clinically considered a syringocystadenoma papilliferum, the excised lesion contained multiple dermal nodules that exhibited nearly all stages of follicular differentiation. The periodicity of the follicular proliferations was akin to normal terminal hair, and a prominent perifollicular sheath surrounded each. This benign lesion of abortive hair follicles was unassociated with any established genodermatous syndrome or other adnexal neoplasm.
各种形式的非黑素细胞痣(错构瘤)通常见于儿科患者,而 Jadassohn 皮脂腺痣是最常见的具有未分化毛囊皮脂腺单位的痣。我们报告了一种独特的先天性毛囊痣,尽管有众多其他类型,但它不符合任何先前描述的毛囊肿瘤的标准。临床上认为是乳头状汗腺囊腺瘤,切除的病变包含多个真皮结节,这些结节几乎呈现出毛囊分化的所有阶段。毛囊增殖的周期性类似于正常终毛,并且每个毛囊周围都有一个明显的毛囊周鞘。这种发育不全毛囊的良性病变与任何已确定的遗传性皮肤病综合征或其他附属器肿瘤无关。