Luo Di-Qing, Huang Chang-Zheng, Xie Wen-Lin, Xu Feng-Feng, Mo Li-Qiu
*Department of Dermatology, Huangpu Hospital of The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; †Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Departments of ‡Pathology, §Surgery, and ¶Anesthesiology, Huangpu Hospital of The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Am J Dermatopathol. 2015 Feb;37(2):167-70. doi: 10.1097/DAD.0000000000000040.
Eccrine nevus shows increase in number or size of eccrine glands, whereas hair follicle nevus is composed of densely packed normal vellus hairs, and eccrine-pilar angiomatous nevus reveals increase of eccrine, pilar, and angiomatous structures. No case with increased number of both eccrine glands and hair follicles only in the dermis has been previously reported. A 10-month-old girl presented with cutaneous hamartoma with overlying skin hyperpigmentation on her left hypochondrium since 3 months of age, in whom the lesion was completely excised. Histopathology demonstrated evidently increased number of both eccrine glands and hair follicles in the dermis with reactive hyperplasia of collagen fibers. No recurrence occurred after the tumor was completely excised. A term "hybrid eccrine gland and hair follicle hamartoma" is proposed for this unique lesion.
小汗腺痣表现为小汗腺数量或大小增加,而毛囊痣由密集排列的正常毳毛组成,小汗腺毛囊血管瘤性痣则显示小汗腺、毛囊和血管结构增加。此前尚未有仅真皮内小汗腺和毛囊数量均增加的病例报道。一名10个月大的女孩自3个月大起,左季肋部出现伴有皮肤色素沉着的皮肤错构瘤,该病变已被完整切除。组织病理学显示真皮内小汗腺和毛囊数量明显增加,胶原纤维呈反应性增生。肿瘤完整切除后未复发。为此独特病变提出“混合性小汗腺和毛囊错构瘤”这一术语。