Chen Allan Y, Lee Haidy, Hartman Jonathan, Greco Claudia, Ryu Janice K, O'Donnell Robert, Boggan James
Department of Radiation Oncology , University of California-Davis Medical Center, Sacramento, CA 95817, USA.
AJNR Am J Neuroradiol. 2005 Jan;26(1):160-2.
We report a case of a supratentorial primitive neuroectodermal tumor (PNET) that occurred 12 years after cranial irradiation for a grade II astrocytoma. Neuroimaging was unable to distinguish between a recurrence of the original neoplasm and the development of a new, distinct entity. Pathologic review assisted by immunohistochemical staining, however, revealed a high-grade PNET. Although rare, PNET needs to be included in the differential diagnoses for previously irradiated patients, who develop recurrent brain tumors in the presence of uncharacteristic imaging features.
我们报告了一例幕上原始神经外胚层肿瘤(PNET),该肿瘤发生在一名曾因II级星形细胞瘤接受颅脑放疗12年后。神经影像学无法区分原肿瘤复发与新的、不同实体的形成。然而,在免疫组化染色辅助下的病理检查显示为高级别PNET。尽管罕见,但对于先前接受过放疗且出现不典型影像学特征的复发性脑肿瘤患者,PNET需要纳入鉴别诊断。