Klisch J, Husstedt H, Hennings S, von Velthoven V, Pagenstecher A, Schumacher M
Department of Neuroradiology, University of Freiburg, Germany.
Neuroradiology. 2000 Jun;42(6):393-8. doi: 10.1007/s002340000318.
We report the clinical and pathological findings of supratentorial primitive neuroectodermal tumours (PNETs). These are rare, poorly differentiated, highly malignant neoplasms occurring primarily in young individuals. They frequently show dissemination to the spinal cord and sometimes also beyond neuraxis. Preoperative radiological diagnosis is difficult, due to the nonspecific CT and MRI characteristics. Our findings indicate that diffusion-weighted imaging (DWI) can be used to show the solid portion of the tumour preoperatively and to monitor postsurgical recovery. We describe the MRI findings in three patients with histologically confirmed supratentorial PNET, focussing on the role of DWI for improving the specificity of radiological diagnosis.
我们报告幕上原始神经外胚层肿瘤(PNETs)的临床和病理表现。这些肿瘤罕见,分化差,高度恶性,主要发生于年轻人。它们常扩散至脊髓,有时也超出神经轴范围。由于CT和MRI表现不具特异性,术前放射学诊断困难。我们的研究结果表明,弥散加权成像(DWI)可用于术前显示肿瘤的实性部分,并监测术后恢复情况。我们描述了3例经组织学证实的幕上PNET患者的MRI表现,重点关注DWI在提高放射学诊断特异性方面的作用。