Naber C K, Bauhofer A, Block M, Buerke M, Erbel R, Graninger W, Herrmann M, Horstkotte D, Kern P, Lode H, Mehlhorn U, Meyer J, Mügge A, Niebel J, Peters G, Shah P M, Werdan K
Klinik für Kardiologie, Universitätsklinikum Essen.
MMW Fortschr Med. 2004 Dec 9;146(Suppl 3-4):123-35.
Microbe-induced (infectious) endocarditis is an endovascular infection, caused mainly by bacteria, of cardiovascular structures. The major predilection site are the native heart valves, but involvement of implanted intracardiac foreign material is increasingly being seen. The mortality rate of infectious endocarditis depends on clinical factors and the causal agent, but also on the time of the establishment of the diagnosis and the initiation of appropriate treatment. In Germany, the current mortality rate ranges up to 18%. Between January 2003 and July 2004, with the aim of improving patient care and thus the outcome of this condition, a guideline commission worked out recommendations for the diagnosis, treatment and management of the disease for the use of general practitioners and hospital physicians, in particular microbiologists, infectiologists, cardiologists and cardiac surgeons. The basis for this guideline was the systematic search through the literature of the European guideline. On the 16th and 28th of June 2004, the entire guideline was formerly approved in a nominal group process.
微生物引起的（感染性）心内膜炎是一种主要由细菌导致的心血管结构的血管内感染。主要好发部位是自身心脏瓣膜，但植入的心内异物受累情况也越来越常见。感染性心内膜炎的死亡率取决于临床因素、病原体，还取决于诊断确立时间及恰当治疗的开始时间。在德国，目前死亡率高达18%。2003年1月至2004年7月期间，为改善患者护理从而改善该病的治疗结果，一个指南委员会为全科医生及医院医生，尤其是微生物学家、感染病学家（传染病专家）、心脏病学家及心脏外科医生制定了关于该病诊断、治疗及管理的建议。该指南的依据是对欧洲指南文献的系统检索。2004年6月16日和28日，整个指南在一次名义群体决策过程中获得正式批准。
