Cebrián L, Rodríguez J C, Escribano I, Cascales E, López-Lozano J M, Royo G
S. Microbiology, Hospital General Universitario de Elche, Universidad Miguel Hernández, 03203 Elche, Spain.
Int J Antimicrob Agents. 2005 Feb;25(2):173-6. doi: 10.1016/j.ijantimicag.2004.09.017.
The effect of applying various criteria for elimination of repeated isolates in the same patient on the prevalence and antibiotic susceptibility of microorganisms frequently associated with urinary infections were analyzed. When time criteria were applied, there was a decrease in the number of isolates of 13.4-27.5%, whereas when variations in antibiotic susceptibility were considered, between 4.3 and 20.3% of the isolates were eliminated. The absolute number of isolates varied considerably depending on which of these two criteria were used, but neither criterion was seen to modify significantly the antibiotic susceptibility of these microorganisms and this confirms the recommendations of the NCCLS for this group of pathogens.
分析了采用各种标准消除同一患者重复分离株对泌尿系统感染常见微生物的流行率和抗生素敏感性的影响。应用时间标准时,分离株数量减少了13.4%至27.5%,而考虑抗生素敏感性差异时,4.3%至20.3%的分离株被消除。根据使用这两种标准中的哪一种,分离株的绝对数量差异很大,但这两种标准均未显著改变这些微生物的抗生素敏感性,这证实了美国国家临床实验室标准委员会(NCCLS)针对这类病原体的建议。