Macsai Marian S
Division of Ophthalmology, Evanston Northwestern Healthcare, Chicago, Illinois, USA.
Eye Contact Lens. 2005 Jan;31(1):9-11. doi: 10.1097/01.icl.0000151947.99251.6d.
To report the development of corneal ulcers in two children wearing Paragon Corneal Refractive Therapy (CRT) lenses.
Two case reports of children who developed corneal ulcers when fit with Paragon CRT contact lenses, which were worn nightly, are discussed. Each patient presented with a bacterial corneal ulcer after wearing CRT contact lenses for less than 6 months. In the first patient, Pseudomonas aeruginosa was identified as the causative organism. In the second patient, Haemophilus influenza was cultured from the ulcer.
Both patients were treated with intensive, fortified antibiotics with rapid resolution of the corneal ulcers and preservation of vision. No surgical intervention was required.
Paragon CRT lenses have been approved for use in patients of all ages. When used in children, these lenses may present unique problems. The absolute incidence of bacterial corneal ulcers in patients with CRT lenses are unknown. Severe caution should be used before prescribing CRT lenses for children and informed consent should include potential sight-threatening corneal ulcers.
报告两名佩戴帕拉贡角膜塑形术(CRT)镜片的儿童发生角膜溃疡的情况。
讨论了两例儿童在佩戴每晚使用的帕拉贡CRT隐形眼镜时发生角膜溃疡的病例报告。每名患者在佩戴CRT隐形眼镜不到6个月后出现细菌性角膜溃疡。在第一例患者中,铜绿假单胞菌被确定为病原体。在第二例患者中,从溃疡处培养出流感嗜血杆菌。
两名患者均接受了强化的、高浓度抗生素治疗,角膜溃疡迅速消退,视力得以保留。无需手术干预。
帕拉贡CRT镜片已被批准用于所有年龄段的患者。在儿童中使用时,这些镜片可能会出现独特的问题。佩戴CRT镜片的患者发生细菌性角膜溃疡的绝对发生率尚不清楚。在为儿童开CRT镜片处方前应极其谨慎,知情同意应包括潜在的威胁视力的角膜溃疡。