Galentine P G, Cohen E J, Laibson P R, Adams C P, Michaud R, Arentsen J J
Arch Ophthalmol. 1984 Jun;102(6):891-4. doi: 10.1001/archopht.1984.01040030711025.
We reviewed the experience with ulcerative keratitis associated with contact lens wear at Wills Eye Hospital, Philadelphia, from Jan 1, 1978 through July 1, 1983. Of the 322 cases of ulcerative keratitis, 56 cases (17%) were associated with the use of contact lenses. Twenty-nine (52%) of the 56 cases of contact lens-associated ulcers were culture positive. Pseudomonas was the most common isolate, occurring in 13 (23%) of the 56 cases. Staphylococcus species were the second most common, occurring in 11 (20%) of the 56 cases. In this series, contact lens-associated ulcers were seen frequently in those wearing soft lenses (48/56 cases or 86%) and in those wearing aphakic lenses (32/56 cases or 57%). Contact lens use is an increasingly important risk factor for the development of corneal ulcers. Prompt, appropriate, and intensive treatment is necessary to prevent visual loss.
我们回顾了1978年1月1日至1983年7月1日期间在费城威尔斯眼科医院发生的与隐形眼镜佩戴相关的溃疡性角膜炎病例。在322例溃疡性角膜炎病例中，56例（17%）与隐形眼镜的使用有关。56例与隐形眼镜相关的溃疡病例中，29例（52%）培养呈阳性。铜绿假单胞菌是最常见的分离菌，在56例病例中有13例（23%）出现。葡萄球菌属是第二常见的，在56例病例中有11例（20%）出现。在该系列中，软性隐形眼镜佩戴者（48/56例，占86%）和无晶状体隐形眼镜佩戴者（32/56例，占57%）中经常出现与隐形眼镜相关的溃疡。隐形眼镜的使用是角膜溃疡发生的一个日益重要的危险因素。为防止视力丧失，及时、适当和强化治疗是必要的。
