Two cases of orbital adenocarcinoma treated with heavy charged carbon particle irradiation.

作者信息

Hirai Aki, Mizota Atsushi, Mine Seiichiro, Mizoe Jun-etsu

机构信息

Department of Ophthalmology and Visual Science, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2005 Jun;243(6):610-4. doi: 10.1007/s00417-004-1003-y. Epub 2005 Jan 26.

DOI:10.1007/s00417-004-1003-y

PMID:15672254

Abstract

BACKGROUND

Orbital adenocarcinoma is a relatively rare, primary orbital malignant epithelial tumor, and shares the poor prognosis of orbital adenoid cystic carcinoma. We report the cases of two patients with orbital adenocarcinoma who were treated with heavy charged carbon particle irradiation and followed up for more 6 years.

METHOD

Two patients with orbital adenocarcinoma, 62 and 74 years old, received 57.6 GyE of heavy charged particle irradiation therapy.

RESULTS

In both cases, the size of the tumor gradually decreased after carbon ion irradiation therapy. No recurrences or metastasis of the tumor were found for more than 6 years.

CONCLUSION

Orbital adenocarcinoma has a poor prognosis in general. Two patients with orbital adenocarcinoma were treated with heavy charged carbon particle irradiation therapy and had a relatively good outcome and good prognosis. We believe that heavy charged carbon particle irradiation therapy is a promising therapy for orbital adenoid cystic carcinoma and adenocarcinoma.

摘要