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物质使用和男性性别作为死亡和自杀的风险因素——故意自伤后5年随访研究

Substance use and male gender as risk factors for deaths and suicide--a 5-year follow-up study after deliberate self-harm.

作者信息

Suominen Kirsi, Isometsä Erkki, Haukka Jari, Lönnqvist Jouko

机构信息

Dept. of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2004 Sep;39(9):720-4. doi: 10.1007/s00127-004-0796-7.

Abstract

OBJECTIVE

The aim of this study was to determine the mortality by suicide and other causes of death in a cohort of suicide attempters and identify predictive factors, including contact to healthcare after the attempt.

METHOD

All consecutive 1198 deliberate self-harm patients treated in hospital emergency rooms in Helsinki during a 12-month period were identified. Data were gathered on healthcare contacts preceding and following the index attempt, and cause-specific mortality over a 5-year period.

RESULTS

By the end of the 5-year follow-up period, 171 (14%) of the patients had died. A total of 57 (5%) had committed suicide. The age- and sex-adjusted risk for suicide among deliberate self-harm patients was 40-fold, and for death overall tenfold, compared to general population during the 5-year follow-up period. Risk factors for subsequent suicide were a diagnosis of substance use disorder, male gender and previous suicide attempts. A diagnosis of substance use disorder and male gender predicted death. Furthermore, male gender and substance use disorders had a strong interaction for both classes of death.

CONCLUSIONS

The findings of this study suggest that deliberate self-harm patients have a high risk for both suicide and other causes of death. Male gender and substance use disorders are significant risk factors for both later suicide and other causes of death. Male suicide attempters with substance use disorders have remarkably high total and suicide mortality.

摘要

目的

本研究旨在确定自杀未遂者队列中的自杀死亡率及其他死因,并识别预测因素,包括自杀未遂后的医疗接触情况。

方法

确定了在赫尔辛基医院急诊室接受治疗的连续1198例故意自伤患者,这些患者均在12个月内就诊。收集了索引自杀未遂事件前后的医疗接触数据以及5年期间的死因特异性死亡率数据。

结果

到5年随访期结束时,171例(14%)患者死亡。共有57例(5%)自杀。在5年随访期内,故意自伤患者经年龄和性别调整后的自杀风险是普通人群的40倍,总体死亡风险是普通人群的10倍。后续自杀的危险因素包括物质使用障碍诊断、男性性别和既往自杀未遂史。物质使用障碍诊断和男性性别可预测死亡。此外,男性性别和物质使用障碍在两类死亡中均存在强烈的相互作用。

结论

本研究结果表明,故意自伤患者存在自杀及其他死因的高风险。男性性别和物质使用障碍是后期自杀及其他死因的重要危险因素。患有物质使用障碍的男性自杀未遂者的总死亡率和自杀死亡率显著较高。

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