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在医疗急救中心接受检查的自杀未遂者的长期自杀风险因素:一项 32 年随访研究的结果。

Long-term risk factors for suicide in suicide attempters examined at a medical emergency in patient unit: results from a 32-year follow-up study.

机构信息

Department of Clinical Sciences, Lund University, Lund, Sweden

Region Skåne, Clinical Psychiatric Research Center, Lund, Sweden.

出版信息

BMJ Open. 2020 Oct 31;10(10):e038794. doi: 10.1136/bmjopen-2020-038794.

Abstract

OBJECTIVES

The overall aim of this study is to gain greater knowledge about the risk of suicide among suicide attempters in a very long-term perspective. Specifically, to investigate possible differences in clinical risk factors at short (≤5 years) versus long term (>5 years), with the hypothesis that risk factors differ in the shorter and longer perspective.

DESIGN

Prospective study with register-based follow-up for 21-32 years.

SETTING

Medical emergency inpatient unit in the south of Sweden.

PARTICIPANTS

1044 individuals assessed by psychiatric consultation when admitted to medical inpatient care for attempted suicide during 1987-1998.

OUTCOME MEASURES

Suicide and all-cause mortality.

RESULTS

At follow-up, 37.6% of the participants had died, 7.2% by suicide and 53% of these within 5 years of the suicide attempt. A diagnosis of psychosis at baseline represented the risk factor with the highest HR at long-term follow-up, that is, >5 years, followed by major depression and a history of attempted suicide before the index attempt. The severity of a suicide attempt as measured by SIS (Suicide Intent Scale) showed a non-proportional association with the hazard for suicide over time and was a relevant risk factor for suicide only within the first 5 years after an attempted suicide.

CONCLUSIONS

The risk of suicide after a suicide attempt persists for up to 32 years after the index attempt. A baseline diagnosis of psychosis or major depression or earlier suicide attempts continued to be relevant risk factors in the very long term. The SIS score is a better predictor of suicide risk at short term, that is, within 5 years than at long term. This should be considered in the assessment of suicide risk and the implementation of care for these individuals.

摘要

目的

本研究的总体目标是从长远角度更深入地了解自杀未遂者的自杀风险。具体而言,研究在短期(≤5 年)和长期(>5 年)时可能存在的临床风险因素差异,假设风险因素在较短和较长时间内存在差异。

设计

前瞻性研究,对 1987 年至 1998 年因自杀而住院的患者进行基于登记的 21-32 年随访。

地点

瑞典南部的医疗急诊住院病房。

参与者

1044 名在因自杀企图而住院接受精神科评估的个体。

结局指标

自杀和全因死亡率。

结果

随访期间,37.6%的参与者死亡,7.2%死于自杀,其中 53%在自杀企图后 5 年内死亡。基线时的精神病诊断是长期随访(>5 年)中风险最高的危险因素,其次是重性抑郁和自杀企图史。SIS(自杀意念量表)测量的自杀企图严重程度与自杀风险之间呈非比例关系,且仅在自杀企图后 5 年内与自杀风险相关。

结论

自杀未遂后 32 年内仍存在自杀风险。基线时的精神病或重性抑郁诊断或更早的自杀企图仍然是长期的重要危险因素。SIS 评分在短期(5 年内)比长期更能预测自杀风险。在评估自杀风险和为这些个体提供护理时应考虑到这一点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a13d/7783608/924a81f83ad7/bmjopen-2020-038794f01.jpg

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