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[青少年使用左炔诺孕酮进行紧急避孕]

[Emergency contraception with levonorgestrel in adolescents].

作者信息

Tanchev S, Shentov B

出版信息

Akush Ginekol (Sofiia). 2004;43 Suppl 3:41-4.

Abstract

OBJECTIVE

The aim of the study was to asses effectiveness and adverse reactions in adolescent girls received Postinor (0.75 mg Levonorgestrel) for emergency contraception.

METHOD

Forty-two teenage girls with established regular menstrual cycles for 24 months period and 128 intercourses are included. Excluding criteria are: clinical data for gynecological endocrine diseases, other contraceptive methods used and contraindication for using gestagens. The girls received tablets Postinor containing 0.75 mg levonorgestrel in dosage 1 or 2 pills after non-protected sexual contact. Before the study the girls are examined for their knowledge about fertile period of the menstrual cycle, opportunities of hormonal contraception and about their ability to make adequate decisions in unpredicted situations and complications of the unprotected or inadequate protected intercourse.

RESULTS

No one pregnancy occurred during the study period. Main first adverse reactions after receiving Postinor were nausea (12.4%) and intermenstrual bleeding (30.9%), persisting up to three days. Systemic adverse reactions reported from the women were breast tenderness (11.2%), dizziness (6.5%) and headache (5.6%). These side effects were mild and did not require treatment.

CONCLUSION

Emergency contraception with Levonorgestrel is effective, with less contraindications compared with other emergency contraception methods. Postinor is available and reliable contraceptive medication.

摘要

目的

本研究旨在评估青春期女孩服用复方左炔诺孕酮片(0.75毫克左炔诺孕酮)进行紧急避孕的有效性和不良反应。

方法

纳入42名月经周期规律达24个月且有128次性交经历的少女。排除标准为:妇科内分泌疾病的临床资料、使用的其他避孕方法以及使用孕激素的禁忌证。这些女孩在无保护性行为后服用含0.75毫克左炔诺孕酮的复方左炔诺孕酮片,剂量为1片或2片。在研究前,对女孩们进行检查,了解她们对月经周期排卵期的知识、激素避孕的机会以及在意外情况和无保护或保护不当性交并发症时做出适当决定的能力。

结果

研究期间无一人怀孕。服用复方左炔诺孕酮片后主要的首次不良反应为恶心(12.4%)和经间期出血(30.9%),持续长达三天。女性报告的全身不良反应有乳房压痛(11.2%)、头晕(6.5%)和头痛(5.6%)。这些副作用较轻,无需治疗。

结论

左炔诺孕酮紧急避孕有效,与其他紧急避孕方法相比禁忌证较少。复方左炔诺孕酮片是一种可用且可靠的避孕药物。

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