Szymańska-Chabowska Anna, Skoczyńska Anna, Chlebda Ewa, Andrzejak Ryszard
Katedra i Klinika Chorób Wewnetrznych, Zawodowych i Nadciśnienia Tetniczego AM we Wrocławiu.
Pol Arch Med Wewn. 2004 Aug;112(2):953-9.
In this paper a case of 46-year-old woman suffering from the acute intermittent porphyria (AIP) was presented. She developed the chronic renal failure due to the hypertension, reccurent urinary tract infections and neurogenic urinary bladder following the autonomic neuropathy. The patient eventually died in spite of haemodialysis. Skin lesions observed in the last stage of the disease could be an evidence of the possible conversion of AIP in variegate porphyria (VP). However, this suspicion is only the hypothesis due to the lack of the adequate enzymatic lab tests.
本文报告了一例46岁患急性间歇性卟啉病（AIP）的女性病例。她因自主神经病变后出现高血压、复发性尿路感染和神经源性膀胱而发展为慢性肾衰竭。尽管进行了血液透析，患者最终还是死亡。在疾病后期观察到的皮肤病变可能是AIP转变为杂合性卟啉病（VP）的证据。然而，由于缺乏充分的酶学实验室检测，这种怀疑只是一种假设。
