Bossi Philippe, Tegnell Anders, Baka Agoritsa, Van Loock Frank, Hendriks Jan, Werner Albrecht, Maidhof Heinrich, Gouvras Georgios
Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg.
Euro Surveill. 2004 Dec 15;9(12):E3-4.
The spore-forming Bacillus anthracis must be considered as one of the most serious potential biological weapons. The recent cases of anthrax caused by a deliberate release reported in 2001 in the United States point to the necessity of early recognition of this disease. Infection in humans most often involves the skin, and more rarely the lungs and the gastrointestinal tract. Inhalational anthrax is of particular interest for possible deliberate release: it is a life-threatening disease and early diagnosis and treatment can significantly decrease the mortality rate. Treatment consists of massive doses of antibiotics and supportive care. Isolation is not necessary. Antibiotics such as ciprofloxacin are recommended for post-exposure prophylaxis during 60 days.
形成孢子的炭疽芽孢杆菌必须被视为最严重的潜在生物武器之一。2001年美国报告的由蓄意释放导致的近期炭疽病例表明了早期识别这种疾病的必要性。人类感染最常累及皮肤,较少累及肺部和胃肠道。吸入性炭疽因可能被蓄意释放而特别受到关注:它是一种危及生命的疾病,早期诊断和治疗可显著降低死亡率。治疗包括大剂量抗生素和支持性护理。无需隔离。建议在暴露后60天内使用环丙沙星等抗生素进行暴露后预防。