Lewden C, Sobesky M, Cabié A, Couppié P, Boulard F, Bissuel F, May T, Morlat P, Chêne G, Lamaury I, Salmon D
Inserm U593 (exU330), 146, rue Léo-Saignat, 33076 Bordeaux cedex, France.
Med Mal Infect. 2004 Jul;34(7):286-92.
The survey "Mortality 2000" had for aim to describe the distribution of causes of death in HIV-infected adults in France.
Hospital wards involved in the management of HIV infection prospectively reported deaths occurring in 2000. The causes of death were documented using a standardized questionnaire.
In French Guyana and the French West Indies the five referent wards reported 81 deaths. The main underlying causes of death were AIDS-related (67%), non-AIDS and non-hepatitis related cancer (9%), cardiovascular disease (7%), bacterial infections (5%), and end stage liver disease (4%). Among AIDS-related deaths, the more frequent diseases were histoplasmosis and toxoplasmosis in Guyana and atypical mycobacterial infection, tuberculosis, and cytomegalovirus disease in the West Indies. Median age was 43 years, transmission of HIV infection was heterosexual in 79%; 56% lived in poor socio-economic conditions, and 30% were born abroad. One out of five had been recently diagnosed with HIV infection and one out of three had never received antiretroviral treatment.
In 2000, two in three death cases in HIV-infected adults were AIDS-related in French Guyana and the French West Indies. Improved strategies for screening HIV infection before the occurrence of AIDS are still needed taking into consideration poor socio-economic and migrant conditions.
“2000年死亡率”调查旨在描述法国感染艾滋病毒的成年人的死因分布情况。
参与艾滋病毒感染管理的医院病房前瞻性报告了2000年发生的死亡病例。使用标准化问卷记录死因。
在法属圭亚那和法属西印度群岛，五个参考病房报告了81例死亡。主要潜在死因与艾滋病相关（67%）、非艾滋病和非肝炎相关癌症（9%）、心血管疾病（7%）、细菌感染（5%）以及终末期肝病（4%）。在与艾滋病相关的死亡病例中，圭亚那较常见的疾病是组织胞浆菌病和弓形虫病，西印度群岛则是非典型分枝杆菌感染、结核病和巨细胞病毒病。中位年龄为43岁，79%的艾滋病毒感染传播途径为异性传播；56%生活在社会经济条件较差的环境中，30%出生在国外。五分之一的人最近被诊断出感染艾滋病毒，三分之一的人从未接受过抗逆转录病毒治疗。
2000年，在法属圭亚那和法属西印度群岛，感染艾滋病毒的成年人中有三分之二的死亡病例与艾滋病相关。鉴于社会经济条件差和移民情况，仍需要改进在艾滋病发生前筛查艾滋病毒感染的策略。
