García García Cosme, Curós Abadal Antoni, Serra Flores Jordi, Tizón Marcos Helena, Carol Ruiz Antoni, Valle Tudela Vicente
Servicio de Cardiología, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain.
Rev Esp Cardiol. 2005 Jan;58(1):20-6.
The aim of this study was to determine the duration of complete atrioventricular block complicating inferior wall acute myocardial infarction after the administration of fibrinolytic therapy.
From 1 January 1992 to 31 January 2002 a total of 449 patients were admitted directly to our hospital with inferior wall acute myocardial infarction in the first 6 hours; 282 of them (64%) received fibrinolytic therapy. Complete atrioventricular block appeared in 39 of these 282 patients (13.8%, group A). Of the 167 patients who did not receive thrombolytic therapy, complete atrioventricular block appeared in 13 (8%, control group). We compared the two groups by analyzing the duration of heart block, time to appearance, hemodynamic repercussion, and treatment required.
On admission, 38% of the patients in group A and 61% (P=NS) of those in the control group had complete atrioventricular block. Median duration of the block was 75 minutes (10 minutes to 48 hours) in group A and 24 hours (15 minutes to 9 days) in the control group (P=.004). After fibrinolytic therapy was administered, median duration of the block was 45 minutes (5 minutes to 48 hours). A temporary pacemaker was implanted in 43% of the group A patients and 84.6% of the control group patients (P=.01).
Complete atrioventricular block appears as a complication of inferior myocardial infarction within the first hours after the event. Duration of the block seems to be shorter in patients treated with fibrinolytic therapy.
本研究旨在确定在接受纤维蛋白溶解疗法后,下壁急性心肌梗死并发完全性房室传导阻滞的持续时间。
从1992年1月1日至2002年1月31日,共有449例患者在发病的最初6小时内直接入住我院,诊断为下壁急性心肌梗死;其中282例(64%)接受了纤维蛋白溶解疗法。在这282例患者中,有39例(13.8%,A组)出现了完全性房室传导阻滞。在未接受溶栓治疗的167例患者中,有13例(8%,对照组)出现了完全性房室传导阻滞。我们通过分析心脏传导阻滞的持续时间、出现时间、血流动力学影响以及所需治疗方法,对两组进行了比较。
入院时,A组38%的患者和对照组61%(P=无显著差异)的患者存在完全性房室传导阻滞。A组传导阻滞的中位持续时间为75分钟(10分钟至48小时),对照组为24小时(15分钟至9天)(P=0.004)。在接受纤维蛋白溶解疗法后,传导阻滞的中位持续时间为45分钟(5分钟至48小时)。A组43%的患者和对照组84.6%的患者植入了临时起搏器(P=0.01)。
完全性房室传导阻滞在事件发生后的最初几小时内作为下壁心肌梗死的并发症出现。接受纤维蛋白溶解疗法的患者中,传导阻滞的持续时间似乎较短。